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PDE6B anticorps (AA 1-190)

PDE6B Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6145363
  • Antigène Voir toutes PDE6B Anticorps
    PDE6B (phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B))
    Épitope
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-190
    Reactivité
    • 13
    • 10
    • 8
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    Humain
    Hôte
    • 13
    • 1
    Lapin
    Clonalité
    • 14
    Polyclonal
    Conjugué
    • 12
    • 1
    • 1
    Cet anticorp PDE6B est non-conjugé
    Application
    • 11
    • 6
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Séquence
    MSLSEEQARS FLDQNPDFAR QYFGKKLSPE NVAAACEDGC PPDCDSLRDL CQVEESTALL ELVQDMQESI NMERVVFKVL RRLCTLLQAD RCSLFMYRQR NGVAELATRL FSVQPDSVLE DCLVPPDSEI VFPLDIGVVG HVAQTKKMVN VEDVAECPHF SSFADELTDY KTKNMLATPI MNGKDVVAVI
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human PDE6B (NP_001138763.1).
    Isotype
    IgG
  • Indications d'application
    WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100
    Commentaires

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    PDE6B (phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B))
    Autre désignation
    PDE6B (PDE6B Produits)
    Synonymes
    anticorps CSNB3, anticorps CSNBAD2, anticorps PDEB, anticorps RP40, anticorps rd1, anticorps PDBS, anticorps RCD-1, anticorps Pdeb, anticorps r, anticorps rd, anticorps rd-1, anticorps rd10, anticorps phosphodiesterase 6B, anticorps phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide, anticorps PDE6B, anticorps Pde6b
    Sujet
    Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.,PDE6B,CSNB3,CSNBAD2,PDEB,RP40,rd1,GMP-PDEbeta,Signal Transduction,Neuroscience,PDE6B
    Poids moléculaire
    66 kDa/98 kDa
    ID gène
    5158
    UniProt
    P35913
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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