PDK3 anticorps (AA 137-406)
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- Antigène Voir toutes PDK3 Anticorps
- PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
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Épitope
- AA 137-406
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PDK3 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- FGFDPFISTN IQYFLDRFYT NRISFRMLIN QHTLLFGGDT NPVHPKHIGS IDPTCNVADV VKDAYETAKM LCEQYYLVAP ELEVEEFNAK APDKPIQVVY VPSHLFHMLF ELFKNSMRAT VELYEDRKEG YPAVKTLVTL GKEDLSIKIS DLGGGVPLRK IDRLFNYMYS TAPRPSLEPT RAAPLAGFGY GLPISRLYAR YFQGDLKLYS MEGVGTDAVI YLKALSSESF ERLPVFNKSA WRHYKTTPEA DDWSNPSSEP RDASKYKAKQ
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Polyclonal Antibodies
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 137-406 of human PDK3 (NP_005382.1).
- Isotype
- IgG
- Top Product
- Discover our top product PDK3 Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000
- Commentaires
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
- Autre désignation
- PDK3 (PDK3 Produits)
- Synonymes
- anticorps pdk3, anticorps PDK3, anticorps 2610001M10Rik, anticorps AI035637, anticorps zgc:158702, anticorps pyruvate dehydrogenase kinase 3, anticorps pyruvate dehydrogenase kinase, isozyme 3a, anticorps pyruvate dehydrogenase kinase, isoenzyme 3, anticorps fragile site, 5-azacytidine type, common, fra(1)(q12), anticorps pyruvate dehydrogenase kinase, isozyme 3b, anticorps PDK3, anticorps Pdk3, anticorps pdk3a, anticorps pdk3, anticorps FRA1J, anticorps pdk3b
- Sujet
- The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle, and thus is one of the major enzymes responsible for the regulation of glucose metabolism. The enzymatic activity of PDH is regulated by a phosphorylation/dephosphorylation cycle, and phosphorylation results in inactivation of PDH. The protein encoded by this gene is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit. This gene is predominantly expressed in the heart and skeletal muscles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,PDK3,CMTX6,GS1-358P8.4,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Warburg Effect,PDK3
- Poids moléculaire
- 46 kDa/48 kDa
- ID gène
- 5165
- UniProt
- Q15120
- Pathways
- Signalisation PI3K-Akt, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, L'effet Warburg
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