PDK4 anticorps (AA 102-411)

N° du produit ABIN6145396

Détail du produit anti-PDK4 anticorps

Antigène: PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

Épitope: AA 102-411

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDK4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: FHEKSPDDQK ALSDFVDTLI KVRNRHHNVV PTMAQGIIEY KDACTVDPVT NQNLQYFLDR FYMNRISTRM LMNQHILIFS DSQTGNPSHI GSIDPNCDVV AVVQDAFECS RMLCDQYYLS SPELKLTQVN GKFPDQPIHI VYVPSHLHHM LFELFKNAMR ATVEHQENQP SLTPIEVIVV LGKEDLTIKI SDRGGGVPLR IIDRLFSYTY STAPTPVMDN SRNAPLAGFG YGLPISRLYA KYFQGDLNLY SLSGYGTDAI IYLKALSSES IEKLPVFNKS AFKHYQMSSE ADDWCIPSRE PKNLAKEVAM

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 102-411 of human PDK4 (NP_002603.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PDK4

Antigène: PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

Autre désignation: PDK4 (PDK4 Produits)

Synonymes: anticorps AV005916, anticorps pyruvate dehydrogenase kinase 4, anticorps pyruvate dehydrogenase kinase, isoenzyme 4, anticorps pdk4, anticorps PDK4, anticorps Pdk4

Sujet: This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.,PDK4,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Warburg Effect,PDK4

Poids moléculaire: 46 kDa

ID gène: 5166

UniProt: Q16654

Pathways: Signalisation PI3K-Akt, Signalisation Hedgehog, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, L'effet Warburg