Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

PFKFB3 anticorps (AA 400-500)

PFKFB3 Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6145485
  • Antigène Voir toutes PFKFB3 Anticorps
    PFKFB3 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3))
    Épitope
    • 15
    • 15
    • 15
    • 11
    • 9
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 400-500
    Reactivité
    • 79
    • 70
    • 65
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    Humain
    Hôte
    • 89
    • 5
    Lapin
    Clonalité
    • 86
    • 10
    Polyclonal
    Conjugué
    • 36
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp PFKFB3 est non-conjugé
    Application
    • 64
    • 40
    • 40
    • 26
    • 15
    • 15
    • 9
    • 9
    • 6
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    LDKSAEEMPY LKCPLHTVLK LTPVAYGCRV ESIYLNVESV CTHRERSEDA KKGPNPLMRR NSVTPLASPE PTKKPRINSF EEHVASTSAA LPSCLPPEVP T
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    A synthetic peptide corresponding to a sequence within amino acids 400-500 of human PFKFB3 (NP_004557.1).
    Isotype
    IgG
    Top Product
    Discover our top product PFKFB3 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:1000,IHC,1:50 - 1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    PFKFB3 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3))
    Autre désignation
    PFKFB3 (PFKFB3 Produits)
    Synonymes
    anticorps IPFK2, anticorps PFK2, anticorps E330010H22Rik, anticorps iPFK-2, anticorps uPFK-2, anticorps PFKFB3, anticorps zgc:73257, anticorps wu:fc31e01, anticorps 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3, anticorps 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 S homeolog, anticorps PFKFB3, anticorps Pfkfb3, anticorps pfkfb3.S, anticorps pfkfb3, anticorps PTRG_09894, anticorps Tsp_06710
    Sujet
    The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.,PFKFB3,IPFK2,PFK2,iPFK-2,Endocrine & Metabolism,Carbohydrate metabolism,AMPK Signaling Pathway,Warburg Effect,PFKFB3
    Poids moléculaire
    57 kDa/58 kDa/59 kDa/60 kDa
    ID gène
    5209
    UniProt
    Q16875
    Pathways
    AMPK Signaling, Regulation of Carbohydrate Metabolic Process
Vous êtes ici:
Support technique