PINK1 anticorps (AA 282-581)

N° du produit ABIN6145665

Détail du produit anti-PINK1 anticorps

Antigène: PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

Épitope: AA 282-581

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PINK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: TSSVPLLPGA LVDYPDVLPS RLHPEGLGHG RTLFLVMKNY PCTLRQYLCV NTPSPRLAAM MLLQLLEGVD HLVQQGIAHR DLKSDNILVE LDPDGCPWLV IADFGCCLAD ESIGLQLPFS SWYVDRGGNG CLMAPEVSTA RPGPRAVIDY SKADAWAVGA IAYEIFGLVN PFYGQGKAHL ESRSYQEAQL PALPESVPPD VRQLVRALLQ REASKRPSAR VAANVLHLSL WGEHILALKN LKLDKMVGWL LQQSAATLLA NRLTEKCCVE TKMKMLFLAN LECETLCQAA LLLCSWRAAL

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 282-581 of human PINK1 (NP_115785.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-PINK1 (ABIN6145665)

Ren, Li, Yan, Ma, Zhou, Xue, Zhang, Liu, Yang, Jia, Zhang, Zhang, Mu, Zhang, Da: "Adiponectin modulates oxidative stress-induced mitophagy and protects C2C12 myoblasts against apoptosis." dans: Scientific reports, Vol. 7, Issue 1, pp. 3209, (2018) (PubMed).

Détails sur PINK1

Antigène: PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

Autre désignation: PINK1 (PINK1 Produits)

Synonymes: anticorps BEST:GH23468, anticorps CG4523, anticorps Dmel\\CG4523, anticorps PINK, anticorps PINK1, anticorps dPINK1, anticorps dPink1, anticorps pink1, anticorps wu:fc39e12, anticorps zgc:101729, anticorps BRPK, anticorps PARK6, anticorps 1190006F07Rik, anticorps AU042772, anticorps AW557854, anticorps mFLJ00387, anticorps PTEN-induced putative kinase 1, anticorps PTEN induced putative kinase 1, anticorps Pink1, anticorps PINK1, anticorps pink1

Sujet: This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease.,PINK1,BRPK,PARK6,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Autophagy,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Mitophagy fission and fusion,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,Neurodegenerative Diseases Markers,Cardiovascular,Heart,Cardiac metabolism,Mitochondrial Control of Autophagy,PINK1

Poids moléculaire: 30 kDa/62 kDa

ID gène: 65018

UniProt: Q9BXM7

Pathways: Autophagy