PKLR anticorps (AA 446-556)

N° du produit ABIN6145710

Détail du produit anti-PKLR anticorps

Antigène: PKLR (Pyruvate Kinase, Liver and RBC (PKLR))

Épitope: AA 446-556

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKLR est non-conjugé

Application: Western Blotting (WB)

Séquence: PLSRDPTEVT AIGAVEAAFK CCAAAIIVLT TTGRSAQLLS RYRPRAAVIA VTRSAQAARQ VHLCRGVFPL LYREPPEAIW ADDVDRRVQF GIESGKLRGF LRVGDLVIVV T

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 446-556 of human PKLR (NP_000289.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PKLR

Antigène: PKLR (Pyruvate Kinase, Liver and RBC (PKLR))

Autre désignation: PKLR (PKLR Produits)

Synonymes: anticorps PK1, anticorps PKL, anticorps PKR, anticorps PKRL, anticorps RPK, anticorps Pklg, anticorps wu:fd15e01, anticorps wu:fi37e08, anticorps pk1, anticorps PKLR, anticorps Pk-1, anticorps Pk1, anticorps R-PK, anticorps pklr, anticorps pyruvate kinase L/R, anticorps pyruvate kinase, liver and RBC, anticorps pyruvate kinase, liver and RBC L homeolog, anticorps pyruvate kinase liver and red blood cell, anticorps pyruvate kinase PKLR-like, anticorps PKLR, anticorps Pklr, anticorps pklr, anticorps pklr.L, anticorps LOC100621940

Sujet: The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.,PKLR,PK1,PKL,PKR,PKRL,RPK,Cancer,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,PKLR

Poids moléculaire: 58 kDa/61 kDa

ID gène: 5313

UniProt: P30613

Pathways: Ribonucleoside Biosynthetic Process