E-cadherin anticorps (AA 381-481)
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- Antigène Voir toutes E-cadherin (CDH1) Anticorps
- E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))
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Épitope
- AA 381-481
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp E-cadherin est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificité
- This antibody reacts to Cadherin 1, Type 1, E-cadherin (epithelial) (CDH1).
- Purification
- Protein A Chromatography
- Immunogène
- Recombinant protein, CDH1 (NP_004351, 381 a.a. ~ 481 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Genename: CDH1
- Clone
- 3F4
- Isotype
- IgG1
- Top Product
- Discover our top product CDH1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- PBS, pH 7.2
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
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Downregulation of p53 drives autophagy during human trophoblast differentiation." dans: Cellular and molecular life sciences : CMLS, Vol. 75, Issue 10, pp. 1839-1855, (2018) (PubMed).
: "
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Downregulation of p53 drives autophagy during human trophoblast differentiation." dans: Cellular and molecular life sciences : CMLS, Vol. 75, Issue 10, pp. 1839-1855, (2018) (PubMed).
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- Antigène
- E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))
- Autre désignation
- CD324 / Cadherin-1 (CDH1 Produits)
- Synonymes
- anticorps Arc-1, anticorps CD324, anticorps CDHE, anticorps ECAD, anticorps LCAM, anticorps UVO, anticorps E-cadherin, anticorps cdh1, anticorps si:dz180o5.2, anticorps uvo, anticorps lcam, anticorps E-Cad, anticorps XBcad, anticorps l-cam, anticorps xcdh1, anticorps cdhc-A, anticorps xb-cad, anticorps XTCAD-1, anticorps c-cadherin, anticorps cadherin-1, anticorps uvomorulin, anticorps XB-cadherin, anticorps arc-1, anticorps cd324, anticorps cdhe, anticorps ecad, anticorps AA960649, anticorps E-cad, anticorps Ecad, anticorps L-CAM, anticorps Um, anticorps cadherin 1, anticorps si:busm1-180o5.2, anticorps cadherin 1, type 1, E-cadherin (epithelial), anticorps cadherin 1, type 1 S homeolog, anticorps CDH1, anticorps si:busm1-180o5.2, anticorps cdh1, anticorps Cdh1, anticorps cdh1.S
- Sujet
- E Cadherin (CDH1) is a classical cadherin from the cadherin superfamily. It is a calcium dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.Synonyms: CAM 120/80, CDH1, CDHE, E-cadherin, Epithelial cadherin, UVO, Uvomorulin
- ID gène
- 999
- NCBI Accession
- NP_004351
- UniProt
- P12830
- Pathways
- Signalisation WNT, Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation
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