PPARD anticorps (AA 102-361)

N° du produit ABIN6146002

Détail du produit anti-PPARD anticorps

Antigène: PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))

Épitope: AA 102-361

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPARD est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: IRMKLEYEKC ERSCKIQKKN RNKCQYCRFQ KCLALGMSHN AIRFGRMPEA EKRKLVAGLT ANEGSQYNPQ VADLKAFSKH IYNAYLKNFN MTKKKARSIL TGKASHTAPF VIHDIETLWQ AEKGLVWKQL VNGLPPYKEI SVHVFYRCQC TTVETVRELT EFAKSIPSFS SLFLNDQVTL LKYGVHEAIF AMLASIVNKD GLLVANGSGF VTREFLRSLR KPFSDIIEPK FEFAVKFNAL ELDDSDLALF IAAIILCGGE

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 102-361 of human PPARD (NP_803184.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PPARD

Antigène: PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))

Autre désignation: PPARD (PPARD Produits)

Synonymes: anticorps FAAR, anticorps NR1C2, anticorps NUC1, anticorps NUCI, anticorps NUCII, anticorps PPARB, anticorps NUC-1, anticorps Nr1c2, anticorps PPAR-beta, anticorps PPAR-delta, anticorps PPAR[b], anticorps PPARdelta, anticorps Pparb, anticorps Pparb/d, anticorps PPARBETA, anticorps ppard, anticorps pparb, anticorps PPARD, anticorps PPAR-D/B, anticorps peroxisome proliferator activated receptor delta, anticorps peroxisome proliferator activator receptor delta, anticorps peroxisome proliferator activated receptor delta S homeolog, anticorps peroxisome proliferator-activated receptor delta, anticorps PPARD, anticorps Ppard, anticorps ppard.S, anticorps ppard

Sujet: This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation. Alternate splicing results in multiple transcript variants.,PPARD,FAAR,NR1C2,NUC1,NUCI,NUCII,PPARB,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Endocrine and metabolic diseases,Obesity,Cardiovascular,Heart,Cardiac metabolism,PPARD

Poids moléculaire: 38 kDa/40 kDa/45 kDa/49 kDa

ID gène: 5467

UniProt: Q03181

Pathways: Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Monocarboxylic Acid Catabolic Process, Smooth Muscle Cell Migration, Positive Regulation of fat Cell Differentiation