PSTPIP1 anticorps (AA 157-416)
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- Antigène Voir toutes PSTPIP1 Anticorps
- PSTPIP1 (Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))
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Épitope
- AA 157-416
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PSTPIP1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- AFERISANGH QKQVEKSQNK ARQCKDSATE AERVYRQSIA QLEKVRAEWE QEHRTTCEAF QLQEFDRLTI LRNALWVHSN QLSMQCVKDD ELYEEVRLTL EGCSIDADID SFIQAKSTGT EPPAPVPYQN YYDREVTPLT SSPGIQPSCG MIKRFSGLLH GSPKTTSLAA SAASTETLTP TPERNEGVYT AIAVQEIQGN PASPAQEYRA LYDYTAQNPD ELDLSAGDIL EVILEGEDGW WTVERNGQRG FVPGSYLEKL
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Polyclonal Antibodies
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 157-416 of human PSTPIP1 (NP_003969.2).
- Isotype
- IgG
- Top Product
- Discover our top product PSTPIP1 Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- Commentaires
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- PSTPIP1 (Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))
- Autre désignation
- PSTPIP1 (PSTPIP1 Produits)
- Synonymes
- anticorps cd2bp1, anticorps cd2bp1l, anticorps cd2bp1s, anticorps h-pip, anticorps papas, anticorps pstpip, anticorps PSTPIP1, anticorps CD2BP1, anticorps CD2BP1L, anticorps CD2BP1S, anticorps H-PIP, anticorps PAPAS, anticorps PSTPIP, anticorps def-2, anticorps proline-serine-threonine phosphatase interacting protein 1, anticorps proline-serine-threonine phosphatase interacting protein 1 S homeolog, anticorps proline-serine-threonine phosphatase-interacting protein 1, anticorps PSTPIP1, anticorps pstpip1.S, anticorps pstpip1, anticorps Pstpip1
- Sujet
- This gene encodes a cytoskeletal protein that is highly expressed in hemopoietic tissues. This protein functions via its interaction with several different proteins involved in cytoskeletal organization and inflammatory processes. It binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, downregulating CD2-triggered adhesion. It binds PEST-type protein tyrosine phosphatases (PTP) and directs them to c-Abl kinase to mediate c-Abl dephosphorylation, thereby, regulating c-Abl activity. It also interacts with pyrin, which is found in association with the cytoskeleton in myeloid/monocytic cells and modulates immunoregulatory functions. Mutations in this gene are associated with PAPA (pyogenic sterile arthritis, pyoderma gangrenosum, and acne) syndrome. It is hypothesized that the disease-causing mutations compromise physiologic signaling necessary for the maintenance of a proper inflammatory response.,PSTPIP1,CD2BP1,CD2BP1L,CD2BP1S,H-PIP,PAPAS,PSTPIP,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,PSTPIP1
- Poids moléculaire
- 45 kDa/47 kDa
- ID gène
- 9051
- UniProt
- O43586
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