anticorps GLEPP1, anticorps RPTP-BK, anticorps D28, anticorps PTPBK, anticorps PTPROt, anticorps PTPU2, anticorps PTPoc, anticorps PTPphi, anticorps Ptpn15, anticorps R-PTP-O, anticorps NPHS6, anticorps PTP-OC, anticorps PTP-U2, anticorps PTPROT, anticorps protein tyrosine phosphatase, receptor type O, anticorps protein tyrosine phosphatase, receptor type, O, anticorps PTPRO, anticorps Ptpro
Sujet
This gene encodes a member of the R3 subtype family of receptor-type protein tyrosine phosphatases. These proteins are localized to the apical surface of polarized cells and may have tissue-specific functions through activation of Src family kinases. This gene contains two distinct promoters, and alternatively spliced transcript variants encoding multiple isoforms have been observed. The encoded proteins may have multiple isoform-specific and tissue-specific functions, including the regulation of osteoclast production and activity, inhibition of cell proliferation and facilitation of apoptosis. This gene is a candidate tumor suppressor, and decreased expression of this gene has been observed in several types of cancer.,PTPRO,GLEPP1,NPHS6,PTP-OC,PTP-U2,PTPROT,PTPU2,R-PTP-O,Signal Transduction,PTPRO