RAD18 anticorps (AA 216-495)

N° du produit ABIN6146629

Détail du produit anti-RAD18 anticorps

Antigène: RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))

Épitope: AA 216-495

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD18 est non-conjugé

Application: Western Blotting (WB)

Séquence: INKHLDSCLS REEKKESLRS SVHKRKPLPK TVYNLLSDRD LKKKLKEHGL SIQGNKQQLI KRHQEFVHMY NAQCDALHPK SAAEIVREIE NIEKTRMRLE ASKLNESVMV FTKDQTEKEI DEIHSKYRKK HKSEFQLLVD QARKGYKKIA GMSQKTVTIT KEDESTEKLS SVCMGQEDNM TSVTNHFSQS KLDSPEELEP DREEDSSSCI DIQEVLSSSE SDSCNSSSSD IIRDLLEEEE AWEASHKNDL QDTEISPRQN RRTRAAESAE IEPRNKRNRN

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 216-495 of human Rad18 (NP_064550.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-RAD18 (ABIN6146629)

Guo, He, Liu, Liang, Li, Cai, Lan, Zhou, Wang, Lei: "Ablation of Ggnbp2 impairs meiotic DNA double-strand break repair during spermatogenesis in mice." dans: Journal of cellular and molecular medicine, Vol. 22, Issue 10, pp. 4863-4874, (2018) (PubMed).

Détails sur RAD18

Antigène: RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))

Autre désignation: RAD18 (RAD18 Produits)

Synonymes: anticorps RNF73, anticorps 2810024C04Rik, anticorps Rad18sc, anticorps zgc:55577, anticorps RAD18, anticorps DDBDRAFT_0218120, anticorps DDBDRAFT_0304878, anticorps DDB_0218120, anticorps DDB_0304878, anticorps DKFZp469H0810, anticorps RAD18, E3 ubiquitin protein ligase, anticorps RAD18 E3 ubiquitin protein ligase, anticorps E3 ubiquitin-protein ligase RAD18, anticorps E3 ubiquitin-protein ligase, anticorps DNA repair protein and ATPase, anticorps C3HC4-type zinc finger-containing protein, anticorps RAD18, anticorps Rad18, anticorps rad18

Sujet: The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.,RAD18,RNF73,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,RAD18

Poids moléculaire: 56 kDa

ID gène: 56852

UniProt: Q9NS91