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RAG2 anticorps (AA 258-527)

RAG2 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6146663
  • Antigène Voir toutes RAG2 Anticorps
    RAG2 (Recombination Activating Gene 2 (RAG2))
    Épitope
    • 15
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 258-527
    Reactivité
    • 45
    • 14
    • 13
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 39
    • 7
    Lapin
    Clonalité
    • 41
    • 5
    Polyclonal
    Conjugué
    • 22
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RAG2 est non-conjugé
    Application
    • 20
    • 13
    • 13
    • 12
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    VSSAILTQTN NDEFVIVGGY QLENQKRMIC NIISLEDNKI EIREMETPDW TPDIKHSKIW FGSNMGNGTV FLGIPGDNKQ VVSEGFYFYM LKCAEDDTNE EQTTFTNSQT STEDPGDSTP FEDSEEFCFS AEANSFDGDD EFDTYNEDDE EDESETGYWI TCCPTCDVDI NTWVPFYSTE LNKPAMIYCS HGDGHWVHAQ CMDLAERTLI HLSAGSNKYY CNEHVEIARA LHTPQRVLPL KKPPMKSLRK KGSGKILTPA KKSFLRRLFD
     Réactivité croisée
    Humain, Souris
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 258-527 of human RAG2 (NP_001230715.1).
    Isotype
    IgG
    Top Product
    Discover our top product RAG2 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000
    Commentaires

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    RAG2 (Recombination Activating Gene 2 (RAG2))
    Autre désignation
    RAG2 (RAG2 Produits)
    Synonymes
    anticorps RAG-2, anticorps Rag-2, anticorps rag-2, anticorps zgc:136743, anticorps recombination activating 2, anticorps recombination activating gene 2, anticorps recombination activating gene 2 S homeolog, anticorps RAG2, anticorps Rag2, anticorps rag2, anticorps rag2.S
    Sujet
    This gene encodes a protein that is involved in the initiation of V(D)J recombination during B and T cell development. This protein forms a complex with the product of the adjacent recombination activating gene 1, and this complex can form double-strand breaks by cleaving DNA at conserved recombination signal sequences. The recombination activating gene 1 component is thought to contain most of the catalytic activity, while the N-terminal of the recombination activating gene 2 component is thought to form a six-bladed propeller in the active core that serves as a binding scaffold for the tight association of the complex with DNA. A C-terminal plant homeodomain finger-like motif in this protein is necessary for interactions with chromatin components, specifically with histone H3 that is trimethylated at lysine 4. Mutations in this gene cause Omenn syndrome, a form of severe combined immunodeficiency associated with autoimmune-like symptoms.,RAG2,RAG-2,Epigenetics & Nuclear Signaling,DNA Damage & Repair,RAG2
    Poids moléculaire
    59 kDa
    ID gène
    5897
    UniProt
    P55895
    Pathways
    Chromatin Binding, Production of Molecular Mediator of Immune Response
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