RASGRP1 anticorps (AA 598-797)

N° du produit ABIN6146720

Détail du produit anti-RASGRP1 anticorps

Antigène: RASGRP1 (RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1))

Épitope: AA 598-797

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASGRP1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: PVAPTENNTS VGPVSNLCSL GAKDLLHAPE EGPFTFPNGE AVEHGEESKD RTIMLMGVSS QKISLRLKRA VAHKATQTES QPWIGSEGPS GPFVLSSPRK TAQDTLYVLP SPTSPCPSPV LVRKRAFVKW ENKDSLIKSK EELRHLRLPT YQELEQEINT LKADNDALKI QLKYAQKKIE SLQLEKSNHV LAQMEQGDCS

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 598-797 of human RASGRP1 (NP_005730.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:2000,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RASGRP1

Antigène: RASGRP1 (RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1))

Autre désignation: RASGRP1 (RASGRP1 Produits)

Synonymes: anticorps Rasgrp, anticorps CALDAG-GEFI, anticorps CALDAG-GEFII, anticorps RASGRP, anticorps V, anticorps hRasGRP1, anticorps RAS guanyl releasing protein 1, anticorps Rasgrp1, anticorps RASGRP1

Sujet: This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE).,RASGRP1,CALDAG-GEFI,CALDAG-GEFII,RASGRP,V,hRasGRP1,Cancer,Signal Transduction,G protein signaling,Signal Transduction,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,Neuroscience,Calcium Signaling,RASGRP1

Poids moléculaire: 55 kDa/62 kDa/68 kDa/86 kDa/90 kDa

ID gène: 10125

UniProt: O95267

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway