A2BP1 anticorps (AA 1-130)

N° du produit ABIN6146754

Détail du produit anti-A2BP1 anticorps

Antigène: A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))

Épitope: AA 1-130

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp A2BP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: MLASQGVLLH PYGVPMIVPA APYLPGLIQG NQEAAAAPDT MAQPYASAQF APPQNGIPAE YTAPHPHPAP EYTGQTTVPE HTLNLYPPAQ THSEQSPADT SAQTVSGTAT QTDDAAPTDG QPQTQPSENT

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human RBFOX1 (NP_665900.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur A2BP1

Antigène: A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))

Autre désignation: RBFOX1 (A2BP1 Produits)

Synonymes: anticorps A2BP1, anticorps fox1, anticorps a2bp1, anticorps zgc:103635, anticorps 2BP1, anticorps FOX-1, anticorps FOX1, anticorps HRNBP1, anticorps A2bp, anticorps A2bp1, anticorps Hrnbp1, anticorps fox-1, anticorps RNA binding protein, fox-1 homolog 1, anticorps RNA binding fox-1 homolog 1, anticorps multicopper ferroxidase, anticorps RNA binding protein, fox-1 homolog (C. elegans) 1, anticorps RBFOX1, anticorps rbfox1, anticorps FOX1, anticorps Rbfox1

Sujet: The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.,RBFOX1,2BP1,A2BP1,FOX-1,FOX1,HRNBP1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Neuroscience,Neurodegenerative Diseases,RBFOX1

Poids moléculaire: 40 kDa/42 kDa/44 kDa

ID gène: 54715

UniProt: Q9NWB1