REST anticorps (AA 760-1060)

N° du produit ABIN6146870

Détail du produit anti-REST anticorps

Antigène: REST (RE1-Silencing Transcription Factor (REST))

Épitope: AA 760-1060

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp REST est non-conjugé

Application: Western Blotting (WB)

Séquence: PVKIELSPPI EVVQKEPVQM ELSPPMGVVQ KEPAQREPPP PREPPLHMEP ISKKPPLRKD KKEKSNMQSE RARKEQVLIE VGLVPVKDSW LLKESVSTED LSPPSPPLPK ENLREEASGD QKLLNTGEGN KEAPLQKVGA EEADESLPGL AANINESTHI SSSGQNLNTP EGETLNGKHQ TDSIVCEMKM DTDQNTRENL TGINSTVEEP VSPMLPPSAV EEREAVSKTA LASPPATMAA NESQEIDEDE GIHSHEGSDL SDNMSEGSDD SGLHGARPVP QESSRKNAKE ALAVKAAKGD F

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 760-1060 of human REST/NRSF (NP_001180437.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur REST

Antigène: REST (RE1-Silencing Transcription Factor (REST))

Autre désignation: REST (REST Produits)

Sujet: This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described,REST,NRSF,WT6,XBR,Epigenetics & Nuclear Signaling,Transcription Factors,Neuroscience,Neurodegenerative Diseases,REST

Poids moléculaire: 35 kDa/36 kDa/119 kDa/121 kDa

ID gène: 5978

UniProt: Q13127

Pathways: Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity