Ribonuclease H1 anticorps (AA 1-286)

N° du produit ABIN6146988

Détail du produit anti-Ribonuclease H1 anticorps

Antigène: Ribonuclease H1 (RNASEH1)

Épitope: AA 1-286

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ribonuclease H1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: MSWLLFLAHR VALAALPCRR GSRGFGMFYA VRRGRKTGVF LTWNECRAQV DRFPAARFKK FATEDEAWAF VRKSASPEVS EGHENQHGQE SEAKASKRLR EPLDGDGHES AEPYAKHMKP SVEPAPPVSR DTFSYMGDFV VVYTDGCCSS NGRRRPRAGI GVYWGPGHPL NVGIRLPGRQ TNQRAEIHAA CKAIEQAKTQ NINKLVLYTD SMFTINGITN WVQGWKKNGW KTSAGKEVIN KEDFVALERL TQGMDIQWMH VPGHSGFIGN EEADRLAREG AKQSED

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-286 of human RNASEH1 (NP_002927.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Ribonuclease H1

Antigène: Ribonuclease H1 (RNASEH1)

Autre désignation: RNASEH1 (RNASEH1 Produits)

Synonymes: anticorps H1RNA, anticorps RNH1, anticorps 74/9, anticorps CG8729, anticorps Dmel\\CG8729, anticorps RNase H1, anticorps RnH1, anticorps l(2)43F1-5, anticorps l(2)43Fa, anticorps l(2)k07409, anticorps l(2)k07624, anticorps rnhl, anticorps h1rna, anticorps rnh1, anticorps zgc:91971, anticorps RNASEH1P1, anticorps RNASEH1, anticorps rnaseh1, anticorps Afu1g10020, anticorps Tb07.26A24.40, anticorps ribonuclease H1, anticorps ribonuclease H1 S homeolog, anticorps ribonuclease H1 L homeolog, anticorps ribonuclease HI, anticorps Ribonuclease H1, anticorps RNASEH1, anticorps Rnaseh1, anticorps rnh1, anticorps rnaseh1.S, anticorps rnaseh1, anticorps rnaseh1.L, anticorps AFUA_1G10020, anticorps Tb927.7.4930, anticorps APH_RS00510

Sujet: This gene encodes an endonuclease that specifically degrades the RNA of RNA-DNA hybrids and is necessary for DNA replication and repair. This enzyme is present in both mitochondria and nuclei, which are resulted from translation of a single mRNA with two in-frame initiation start codons. The use of the first start codon produces the mitochondrial isoform and the use of the second start codon produces the nuclear isoform. The production of the mitochondrial isoform is modulated by an upstream open reading frame (uORF) which overlaps the first initiation start codon in human. An alternately spliced transcript variant has been found which encodes a shorter isoform. This gene has three pseudogenes, two of them are at different locations of chromosome 17 and one of them is on chromosome 1q32.2.,RNASEH1,H1RNA,PEOB2,RNH1,Epigenetics & Nuclear Signaling,RNASEH1

Poids moléculaire: 32 kDa

ID gène: 246243

UniProt: O60930