RNF166 anticorps (C-Term)

N° du produit ABIN6147021

Détail du produit anti-RNF166 anticorps

Antigène: RNF166 (Ring Finger Protein 166 (RNF166))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF166 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: GCNKKVTLAK MRVHISSCLK VQEQMANCPK FVPVVPTSQP IPSNIPNRST FACPYCGARN LDQQELVKHC VESHRSDPNR VVCPICSAMP WGDPSYKSAN FLQHLLHRHK FSYDTFVDYS IDEEAAFQAA LALSLSEN

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human RNF166 (NP_849163.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-RNF166 (ABIN6147021)

Lu, Chen, Tung, Chen, Pan, Chang, Cheng, Chen, Wang, Huang, Kang, Chang, Li, Chang, Shih, Lin, Kwan, Tsai: "Identification of genes associated with cortical malformation using a transposon-mediated somatic mutagenesis screen in mice." dans: Nature communications, Vol. 9, Issue 1, pp. 2498, (2019) (PubMed).

Détails sur RNF166

Antigène: RNF166 (Ring Finger Protein 166 (RNF166))

Autre désignation: RNF166 (RNF166 Produits)

Synonymes: anticorps 1110031E24Rik, anticorps AW555115, anticorps Zfp313l, anticorps ring finger protein 166, anticorps ring finger protein 166 L homeolog, anticorps RNF166, anticorps rnf166.L, anticorps Rnf166

Sujet: E3 ubiquitin-protein ligase that promotes the ubiquitination of different substrates. In turn, participates in different biological processes including interferon production or autophagy. Plays a role in the activation of RNA virus-induced interferon-beta production by promoting the ubiquitination of TRAF3 and TRAF6. Plays also a role in the early recruitment of autophagy adapters to bacteria. Mediates 'Lys-29' and 'Lys-33'-linked ubiquitination of SQSTM1 leading to xenophagic targeting of bacteria and inhibition of their replication.,RNF166,Cell Biology & Developmental Biology,Ubiquitin,RNF166

Poids moléculaire: 14 kDa/17 kDa/26 kDa

ID gène: 115992

UniProt: Q96A37