RNF7 anticorps (AA 1-113)

N° du produit ABIN6147047

Détail du produit anti-RNF7 anticorps

Antigène: RNF7 (Ring Finger Protein 7 (RNF7))

Épitope: AA 1-113

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF7 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: MADVEDGEET CALASHSGSS GSKSGGDKMF SLKKWNAVAM WSWDVECDTC AICRVQVMDA CLRCQAENKQ EDCVVVWGEC NHSFHNCCMS LWVKQNNRCP LCQQDWVVQR IGK

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-113 of human RNF7 (NP_055060.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:20 - 1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RNF7

Antigène: RNF7 (Ring Finger Protein 7 (RNF7))

Autre désignation: RNF7 (RNF7 Produits)

Synonymes: anticorps CKBBP1, anticorps ROC2, anticorps SAG, anticorps Rbx2, anticorps ring finger protein 7, anticorps RNF7, anticorps Rnf7

Sujet: The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.,RNF7,CKBBP1,ROC2,SAG,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,Endocrine & Metabolism,RNF7

Poids moléculaire: 9 kDa/10 kDa/11 kDa/12 kDa

ID gène: 9616

UniProt: Q9UBF6

Pathways: Positive Regulation of Endopeptidase Activity