RNF8 anticorps (AA 1-260)

N° du produit ABIN6147049

Détail du produit anti-RNF8 anticorps

Antigène: RNF8 (Ring Finger Protein 8 (RNF8))

Épitope: AA 1-260

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF8 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: MGEPGFFVTG DRAGGRSWCL RRVGMSAGWL LLEDGCEVTV GRGFGVTYQL VSKICPLMIS RNHCVLKQNP EGQWTIMDNK SLNGVWLNRA RLEPLRVYSI HQGDYIQLGV PLENKENAEY EYEVTEEDWE TIYPCLSPKN DQMIEKNKEL RTKRKFSLDE LAGPGAEGPS NLKSKINKVS CESGQPVKSQ GKGEVASTPS DNLDPKLTAL EPSKTTGAPI YPGFPKVTEV HHEQKASNSS ASQRSLQMFK VTMSRILRLK

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human RNF8 (NP_003949.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RNF8

Antigène: RNF8 (Ring Finger Protein 8 (RNF8))

Autre désignation: RNF8 (RNF8 Produits)

Synonymes: anticorps hRNF8, anticorps 3830404E21Rik, anticorps AIP37, anticorps RNF8, anticorps rnf8, anticorps fc66f09, anticorps wu:fc66f09, anticorps zgc:55936, anticorps zgc:77313, anticorps ring finger protein 8, anticorps ring finger protein 8, E3 ubiquitin protein ligase S homeolog, anticorps ring finger protein 8, E3 ubiquitin protein ligase L homeolog, anticorps ring finger protein 8, E3 ubiquitin protein ligase, anticorps RNF8, anticorps Rnf8, anticorps rnf8.S, anticorps rnf8.L, anticorps rnf8

Sujet: The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants.,RNF8,hRNF8,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,RNF8

Poids moléculaire: 10 kDa/50 kDa/55 kDa

ID gène: 9025

UniProt: O76064

Pathways: Production of Molecular Mediator of Immune Response