Hepcidin anticorps (AA 25-85)

N° du produit ABIN614727

Détail du produit anti-Hepcidin anticorps

Antigène: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Épitope: AA 25-85

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Hepcidin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to Hepcidin Antimicrobial Peptide (HAMP).

Purification: Protein A Chromatography

Immunogène: Recombinant protein, HAMP (AAH20612, 25 a.a. ~ 85 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Genename: HAMP

Clone: 1F9

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS, pH 7.2

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Détails sur Hepcidin

Antigène: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Autre désignation: Hepcidin / HAMP (HAMP Produits)

Synonymes: anticorps HEPC, anticorps HFE2B, anticorps LEAP1, anticorps PLTR, anticorps Hepcidin, anticorps Hamp1, anticorps Hepc, anticorps Hepc1, anticorps HAMP, anticorps hepcidin, anticorps hamp1, anticorps hep1, anticorps hepcidin antimicrobial peptide, anticorps hepcidin-like, anticorps hepcidin-1, anticorps Ham percentage, anticorps HAMP, anticorps Hamp, anticorps hamp, anticorps LOC100135935, anticorps LOC106584587

Sujet: Hepcidin, an human antimicrobial peptide, contains a leader sequence, a proteolysis site and a C-terminal 25 amino acid active peptide. This peptide is most active against gram-positive bacteria, but also inhibits the growth of certain yeast and gram-negative bacteria. HAMP also functions as a signaling molecule involved in the maintenance of iron homeostasis. In conjugation with HFE it seems to regulate both intestinal iron absorption and iron storage in macrophages. Mutations in HAMP are found in juvenile hemochromatosis.Synonyms: HEPC, LEAP-1, LEAP1, Liver-expressed antimicrobial peptide, PLTR, Putative liver tumor regressor

ID gène: 57817

NCBI Accession: NP_066998

UniProt: P81172

Pathways: Hormone Activity, Transition Metal Ion Homeostasis