SAG anticorps (AA 1-405)

N° du produit ABIN6147361

Détail du produit anti-SAG anticorps

Antigène: SAG (S-Antigen, Retina and Pineal Gland (Arrestin) (SAG))

Épitope: AA 1-405

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SAG est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: MAASGKTSKS EPNHVIFKKI SRDKSVTIYL GNRDYIDHVS QVQPVDGVVL VDPDLVKGKK VYVTLTCAFR YGQEDIDVIG LTFRRDLYFS RVQVYPPVGA ASTPTKLQES LLKKLGSNTY PFLLTFPDYL PCSVMLQPAP QDSGKSCGVD FEVKAFATDS TDAEEDKIPK KSSVRLLIRK VQHAPLEMGP QPRAEAAWQF FMSDKPLHLA VSLNKEIYFH GEPIPVTVTV TNNTEKTVKK IKAFVEQVAN VVLYSSDYYV KPVAMEEAQE KVPPNSTLTK TLTLLPLLAN NRERRGIALD GKIKHEDTNL ASSTIIKEGI DRTVLGILVS YQIKVKLTVS GFLGELTSSE VATEVPFRLM HPQPEDPAKE SYQDANLVFE EFARHNLKDA GEAEEGKRDK NDVDE

Réactivité croisée: Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-405 of human SAG (NP_000532.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:2000,IHC,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SAG

Antigène: SAG (S-Antigen, Retina and Pineal Gland (Arrestin) (SAG))

Autre désignation: SAG (SAG Produits)

Synonymes: anticorps RP47, anticorps S-AG, anticorps MGC75721, anticorps MGC84416, anticorps sag, anticorps zgc:114197, anticorps SAGMR, anticorps SANTI, anticorps ARR, anticorps sag1, anticorps A930001K18Rik, anticorps Arr1, anticorps Irbp, anticorps arrestin, anticorps S-antigen visual arrestin, anticorps S-antigen, anticorps S-antigen; retina and pineal gland (arrestin), anticorps S-antigen; retina and pineal gland (arrestin) S homeolog, anticorps S-antigen; retina and pineal gland (arrestin) b, anticorps S-antigen, retina and pineal gland (arrestin), anticorps S-antigen; retina and pineal gland (arrestin) L homeolog, anticorps SAG, anticorps PF10_0343, anticorps sag, anticorps sag.S, anticorps sagb, anticorps Sag, anticorps sag.L

Sujet: Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness.,SAG,RP47,S-AG,Signal Transduction,G protein signaling,SAG

Poids moléculaire: 45 kDa

ID gène: 6295

UniProt: P10523

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling