SPTAN1 anticorps (AA 950-1130)

N° du produit ABIN6148403

Détail du produit anti-SPTAN1 anticorps

Antigène: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Épitope: AA 950-1130

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPTAN1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: REQAQSCRQQ VAPTDDETGK ELVLALYDYQ EKSPREVTMK KGDILTLLNS TNKDWWKVEV NDRQGFVPAA YVKKLDPAQS ASRENLLEEQ GSIALRQEQI DNQTRITKEA GSVSLRMKQV EELYHSLLEL GEKRKGMLEK SCKKFMLFRE ANELQQWINE KEAALTSEEV GADLEQVEVL Q

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 950-1130 of human Alpha Fodrin (NP_001123910.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-SPTAN1 (ABIN6148403)

Meng, Zhang, Shi, Zhang, Yuan: "Inhibition of interleukin-6 abolishes the promoting effects of pair housing on post-stroke neurogenesis." dans: Neuroscience, Vol. 307, pp. 160-70, (2016) (PubMed).

Détails sur SPTAN1

Antigène: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Autre désignation: SPTAN1 (SPTAN1 Produits)

Synonymes: anticorps im:7157190, anticorps wu:fa20e05, anticorps wu:fb33g08, anticorps wu:fk32a10, anticorps zgc:112229, anticorps 2610027H02Rik, anticorps Spna-2, anticorps Spna2, anticorps EIEE5, anticorps NEAS, anticorps SPTA2, anticorps A2a, anticorps IPF, anticorps SPECA, anticorps spectrin alpha, non-erythrocytic 1, anticorps spectrin, alpha, non-erythrocytic 1, anticorps SPTAN1, anticorps sptan1, anticorps Sptan1

Sujet: Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.,SPTAN1,EIEE5,NEAS,SPTA2,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Microfilaments,Death Receptor Signaling Pathway,SPTAN1

Poids moléculaire: 282 kDa/284 kDa/285 kDa

ID gène: 6709

UniProt: Q13813

Pathways: Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization