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TBC1D23 anticorps (AA 250-600)

TBC1D23 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6148882
  • Antigène Tous les produits TBC1D23
    TBC1D23 (TBC1 Domain Family, Member 23 (TBC1D23))
    Épitope
    • 4
    • 1
    • 1
    • 1
    AA 250-600
    Reactivité
    • 9
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 9
    Lapin
    Clonalité
    • 9
    Polyclonal
    Conjugué
    • 6
    • 1
    • 1
    • 1
    Cet anticorp TBC1D23 est non-conjugé
    Application
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    SDSKEEVIKF LENTPSSLNI EDIEDLFSLA QYYCSKTPAS FRKDNHHLFG STLLGIKDDD ADLSQALCLA ISVSEILQAN QLQGEGVRFF VVDCRPAEQY NAGHLSTAFH LDSDLMLQNP SEFAQSVKSL LEAQKQSIES GSIAGGEHLC FMGSGREEED MYMNMVLAHF LQKNKEYVSI ASGGFMALQQ HLADINVDGP ENGYGHWIAS TSGSRSSINS VDGESPNGSS DRGMKSLVNK MTVALKTKSV NVREKVISFI ENTSTPVDRM SFNLPWPDRS CTERHVSSSD RVGKPYRGVK PVFSIGDEEE YDTDEIDSSS MSDDDRKEVV NIQTWINKPD VKHHFPCKEV K
     Réactivité croisée
    Humain, Souris
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 250-600 of human TBC1D23 (NP_001186127.1).
    Isotype
    IgG
  • Indications d'application
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    TBC1D23 (TBC1 Domain Family, Member 23 (TBC1D23))
    Autre désignation
    TBC1D23 (TBC1D23 Produits)
    Synonymes
    anticorps RGD1307925, anticorps NS4ATP1, anticorps 4930451A13Rik, anticorps AU015720, anticorps AU043671, anticorps AU043778, anticorps D030022P07Rik, anticorps W51689, anticorps zgc:63756, anticorps TBC1 domain family, member 23, anticorps TBC1 domain family member 23, anticorps Tbc1d23, anticorps TBC1D23, anticorps tbc1d23
    Sujet
    Putative Rab GTPase-activating protein which plays a role in vesicular trafficking. Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, including GOLGA1 and GOLGA4, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles. Together with WDR11 complex facilitates the golgin-mediated capture of vesicles generated using AP-1. Plays a role in brain development, including in cortical neuron positioning (By similarity. May also be important for neurite outgrowth, possibly through its involvement in membrane trafficking and cargo delivery, 2 processes that are essential for axonal and dendritic growth (By similarity. May act as a general inhibitor of innate immunity signaling, strongly inhibiting multiple TLR and dectin/CLEC7A-signaling pathways. Does not alter initial activation events, but instead affects maintenance of inflammatory gene expression several hours after bacterial lipopolysaccharide (LPS challenge (By similarity.,TBC1D23,NS4ATP1,TBC1D23
    Poids moléculaire
    76 kDa/78 kDa
    ID gène
    55773
    UniProt
    Q9NUY8
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