TEK anticorps (AA 500-750)

N° du produit ABIN6148993

Détail du produit anti-TEK anticorps

Antigène: TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Épitope: AA 500-750

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TEK est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: EIVTLNYLEP RTEYELCVQL VRRGEGGEGH PGPVRRFTTA SIGLPPPRGL NLLPKSQTTL NLTWQPIFPS SEDDFYVEVE RRSVQKSDQQ NIKVPGNLTS VLLNNLHPRE QYVVRARVNT KAQGEWSEDL TAWTLSDILP PQPENIKISN ITHSSAVISW TILDGYSISS ITIRYKVQGK NEDQHVDVKI KNATITQYQL KGLEPETAYQ VDIFAENNIG SSNPAFSHEL VTLPESQAPA DLGGGKMLLI A

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 500-750 of human TEK (NP_000450.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-TEK (ABIN6148993)

Huang, Han, Sun, Zhao, Liu, Yuan, Mao, Peng, Liu, Yin, He: "Kv1.3 channel blocker (ImKTx88) maintains blood-brain barrier in experimental autoimmune encephalomyelitis." dans: Cell & bioscience, Vol. 7, pp. 31, (2017) (PubMed).

Chen, Ren, Zhang, Sun, Wang, Li, Zhang, Zhao: "Disorganized vascular structures in sporadic venous malformations: a possible correlation with balancing effect between Tie2 and TGF-β." dans: Scientific reports, Vol. 4, pp. 5457, (2016) (PubMed).

Détails sur TEK

Antigène: TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Autre désignation: TEK (TEK Produits)

Synonymes: anticorps TEK, anticorps DKFZp469E064, anticorps AA517024, anticorps Cd202b, anticorps Hyk, anticorps Tie2, anticorps tie-2, anticorps CD202B, anticorps TIE-2, anticorps TIE2, anticorps VMCM, anticorps VMCM1, anticorps Tie-2, anticorps tie2, anticorps TEK receptor tyrosine kinase, anticorps angiopoietin-1 receptor, anticorps TEK tyrosine kinase, endothelial, anticorps TEK, anticorps LOC100408334, anticorps tek, anticorps Tek

Sujet: This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.,TEK,CD202B,GLC3E,TIE-2,TIE2,VMCM,VMCM1,Tie2,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,Immunology & Inflammation,CD markers,Stem Cells,Endothelial Progenitors,Cardiovascular,Cardiovascular Markers,Endothelial Cells,Angiogenesis,TEK

Poids moléculaire: 109 kDa/121 kDa/125 kDa

ID gène: 7010

UniProt: Q02763

Pathways: Signalisation RTK, Growth Factor Binding