TOP3B anticorps (AA 1-270)

N° du produit ABIN6149394

Détail du produit anti-TOP3B anticorps

Antigène: TOP3B (Topoisomerase (DNA) III beta (TOP3B))

Épitope: AA 1-270

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TOP3B est non-conjugé

Application: Western Blotting (WB)

Séquence: MKTVLMVAEK PSLAQSIAKI LSRGSLSSHK GLNGACSVHE YTGTFAGQPV RFKMTSVCGH VMTLDFLGKY NKWDKVDPAE LFSQAPTEKK EANPKLNMVK FLQVEGRGCD YIVLWLDCDK EGENICFEVL DAVLPVMNKA HGGEKTVFRA RFSSITDTDI CNAMACLGEP DHNEALSVDA RQELDLRIGC AFTRFQTKYF QGKYGDLDSS LISFGPCQTP TLGFCVERHD KIQSFKPETY WVLQAKVNTD KDRSLLLDWD RVRVFDREIA

Réactivité croisée: Humain, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human TOP3B (NP_003926.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TOP3B

Antigène: TOP3B (Topoisomerase (DNA) III beta (TOP3B))

Autre désignation: TOP3B (TOP3B Produits)

Synonymes: anticorps TOP3B1, anticorps top3b, anticorps DNA topoisomerase III beta, anticorps topoisomerase (DNA) III beta, anticorps DNA topoisomerase III beta L homeolog, anticorps TOP3B, anticorps Top3b, anticorps top3b.L

Sujet: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Low expression of this gene may be related to higher survival rates in breast cancer patients. This gene has a pseudogene on chromosome 22. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.,TOP3B,TOP3B1,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Drug resistance,Topoisomerases,TOP3B

Poids moléculaire: 79 kDa/82 kDa/96 kDa

ID gène: 8940

UniProt: O95985