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TP53INP1 anticorps (AA 1-100)

TP53INP1 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6149422
  • Antigène Voir toutes TP53INP1 Anticorps
    TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))
    Épitope
    • 12
    • 10
    • 8
    • 8
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reactivité
    • 54
    • 28
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 61
    Lapin
    Clonalité
    • 52
    • 8
    Polyclonal
    Conjugué
    • 24
    • 6
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp TP53INP1 est non-conjugé
    Application
    • 42
    • 34
    • 31
    • 12
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    MFQRLNKMFV GEVSSSSNQE PEFNEKEDDE WILVDFIDTC TGFSAEEEEE EEDISEESPT EHPSVFSCLP ASLECLADTS DSCFLQFESC PMEESWFITP
     Réactivité croisée
    Souris
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    A synthetic peptide corresponding to a sequence within amino acids 1-100 of human p53 DINP1 (NP_001129205.1).
    Isotype
    IgG
    Top Product
    Discover our top product TP53INP1 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))
    Autre désignation
    TP53INP1 (TP53INP1 Produits)
    Synonymes
    anticorps cb1036, anticorps wu:fb70a09, anticorps wu:fi13h08, anticorps zgc:158431, anticorps TP53INP1, anticorps 2700057G22Rik, anticorps SIP, anticorps SIP18, anticorps SIP27, anticorps Stinp, anticorps Teap, anticorps TP53DINP1, anticorps TP53INP1A, anticorps TP53INP1B, anticorps p53DINP1, anticorps Trp53inp1, anticorps tumor protein p53 inducible nuclear protein 1, anticorps tumor protein p53 inducible nuclear protein 1 S homeolog, anticorps transformation related protein 53 inducible nuclear protein 1, anticorps TP53INP1, anticorps tp53inp1.S, anticorps tp53inp1, anticorps Trp53inp1, anticorps Tp53inp1
    Sujet
    Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response. Possesses both a p53/TP53-independent intracellular reactive oxygen species (ROS regulatory function and a p53/TP53-dependent transcription regulatory function. Positively regulates p53/TP53 and p73/TP73 and stimulates their capacity to induce apoptosis and regulate cell cycle. In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis. Acts as a tumor suppressor by inducing cell death by an autophagy and caspase-dependent mechanism. Can reduce cell migration by regulating the expression of SPARC.,TP53INP1,SIP,TP53DINP1,TP53INP1A,TP53INP1B,Teap,p53DINP1,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Apoptosis,Autophagy,TP53INP1
    Poids moléculaire
    18 kDa/27 kDa
    ID gène
    94241
    UniProt
    Q96A56
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