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CXCR4 anticorps (Extracellular Domain, N-Term)
CXCR4
Reactivité: Humain, Souris, Xenopus laevis
WB, IHC (p), EIA
Hôte: Chèvre
Polyclonal
unconjugated
Détail du produit anti-CXCR4 anticorps
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Antigène
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CXCR4
(Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
Épitope
Tous les épitopes à travers CXCR4 Anticorps.
AA 14-40, Extracellular Domain, N-Term
Reactivité
Toutes les réactivités sur CXCR4 Anticorps
Humain, Souris, Xenopus laevis
Hôte
Toutes les hôtes sur CXCR4 Anticorps
Chèvre
Clonalité
Toutes les clonalités sur CXCR4 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers CXCR4 Anticorps
Cet anticorp CXCR4 est non-conjugé
Application
Tous les applications à travers CXCR4 Anticorps.
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Séquence
YSEEVGSGDY DSNKEPCFRD ENVHFNR
Specificité
This antibody binds to CXCR4 receptor on Mouse spleen leukocytes as determined by Immunocytochemistry.
Réactivité croisée (Details)
Species reactivity (expected):Xenopus, Human. Species reactivity (tested):Mouse
Purification
Immunoaffinity Chromatography
Immunogène
Sequence corresponding to the N-terminal extracellular domain of Mouse CXCR4 receptor. Epitope: aa14-40 Genename: CXCR4
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
1.0 mg/mL
Buffer
PBS, 0.09 % Sodium Azide, 1 mg/mL BSA
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Détails sur CXCR4
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Antigène
CXCR4
(Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
Autre désignation
CD184 / CXCR4 (CXCR4 Produits )
Synonymes
anticorps CD184, anticorps D2S201E, anticorps FB22, anticorps HM89, anticorps HSY3RR, anticorps LAP3, anticorps LCR1, anticorps LESTR, anticorps NPY3R, anticorps NPYR, anticorps NPYRL, anticorps NPYY3R, anticorps WHIM, anticorps Cmkar4, anticorps PB-CKR, anticorps PBSF/SDF-1, anticorps Sdf1r, anticorps CXC-R4-B, anticorps CXCR-4-B, anticorps cd184, anticorps cxcr4, anticorps fb22, anticorps hm89, anticorps hsy3rr, anticorps lap3, anticorps lcr1, anticorps lestr, anticorps npy3r, anticorps npyr, anticorps npyrl, anticorps npyy3r, anticorps xcxcr4, anticorps CXC-R4, anticorps CXCR-4, anticorps d2s201e, anticorps whim, anticorps CXC-R4-A, anticorps CXCR-4-A, anticorps xCXCR4, anticorps CXCR4, anticorps cb403, anticorps zgc:109863, anticorps cb824, anticorps C-X-C motif chemokine receptor 4, anticorps chemokine (C-X-C motif) receptor 4, anticorps C-X-C motif chemokine receptor 4 S homeolog, anticorps C-X-C chemokine receptor type 4, anticorps C-X-C motif chemokine receptor 4 L homeolog, anticorps chemokine (C-X-C motif), receptor 4b, anticorps chemokine (C-X-C motif) receptor 4a, anticorps CXCR4, anticorps Cxcr4, anticorps cxcr4.S, anticorps cxcr4, anticorps LOC100049444, anticorps cxcr4.L, anticorps cxcr4b, anticorps cxcr4a
Sujet
CXCR4, a Chemokine Receptor involved in organ vascularization, neuronal cell migration, and patterning of the central nervous system during development. It binds stromal cell-derived factor 1 (SDF1, also called PBFS) and mediates migration of resting leukocytes and is unique in homing hematopoietic progenitors to bone marrow. These properties suggest that CXCR4 is involved in tumor cell migration and local tumor invasion. It is also an HIV-1 fusion co-factor that allows HIV-1 invasion in diverse human cell types. Although this receptor was initially called Neuropeptide Y3 Receptor, it does not respond to neuropeptide Y. CXCR4 has two isoforms that are produced by alternative splicing.Synonyms: C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, FB22, Fusin, HM89, LCR1, LESTR, Leukocyte-derived seven transmembrane domain receptor, NPYRL, SDF1 receptor, Stromal cell-derived factor 1 receptor
ID gène
7852
NCBI Accession
NP_001008540
UniProt
P61073
Pathways
Regulation of Cell Size , CXCR4-mediated Signaling Events
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