TSC1 anticorps (AA 550-650)

N° du produit ABIN6149609

Détail du produit anti-TSC1 anticorps

Antigène: TSC1 (Tuberous Sclerosis 1 (TSC1))

Épitope: AA 550-650

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSC1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: QAFTPIDLPC GSADESPAGD RECQTSLETS IFTPSPCKIP PPTRVGFGSG QPPPYDHLFE VALPKTAHHF VIRKTEELLK KAKGNTEEDG VPSTSPMEVL D

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 550-650 of human TSC1 (NP_000359.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:1000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-TSC1 (ABIN6149609)

Zheng, Zhou, Zhang, Thu, Xie, Lu, Pang, Xue, Xu, Chen, Chen, Li, Xu: "Anhydroicaritin improves diet-induced obesity and hyperlipidemia and alleviates insulin resistance by suppressing SREBPs activation." dans: Biochemical pharmacology, Vol. 122, pp. 42-61, (2017) (PubMed).

Détails sur TSC1

Antigène: TSC1 (Tuberous Sclerosis 1 (TSC1))

Autre désignation: TSC1 (TSC1 Produits)

Synonymes: anticorps LAM, anticorps TSC, anticorps hamartin, anticorps mKIAA0243, anticorps tsc1, anticorps wu:fc38b04, anticorps fa99f04, anticorps wu:fa99f04, anticorps zgc:63657, anticorps TSC complex subunit 1, anticorps tuberous sclerosis 1, anticorps TSC complex subunit 1b, anticorps TSC complex subunit 1a, anticorps TSC1, anticorps Tsc1, anticorps tsc1b, anticorps tsc1, anticorps tsc1a

Sujet: This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants.,TSC1,LAM,TSC,hamartin,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Tumor suppressors,Signal Transduction,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Cell Cycle,Cell cycle inhibitors,Endocrine & Metabolism,AMPK Signaling Pathway,Insulin Receptor Signaling Pathway,Endocrine and metabolic diseases,Obesity,Akt downstream targets,Regulators,TSC1

Poids moléculaire: 124 kDa/129 kDa

ID gène: 7248

UniProt: Q92574

Pathways: Signalisation RTK, AMPK Signaling, Regulation of Cell Size, Tube Formation