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TSH receptor anticorps (AA 21-253)

TSHR Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6149622
  • Antigène Voir toutes TSH receptor (TSHR) Anticorps
    TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))
    Épitope
    • 16
    • 16
    • 8
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-253
    Reactivité
    • 86
    • 52
    • 36
    • 9
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Humain
    Hôte
    • 74
    • 14
    • 1
    • 1
    Lapin
    Clonalité
    • 75
    • 15
    Polyclonal
    Conjugué
    • 44
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TSH receptor est non-conjugé
    Application
    • 44
    • 40
    • 20
    • 17
    • 13
    • 13
    • 12
    • 8
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    GMGCSSPPCE CHQEEDFRVT CKDIQRIPSL PPSTQTLKLI ETHLRTIPSH AFSNLPNISR IYVSIDVTLQ QLESHSFYNL SKVTHIEIRN TRNLTYIDPD ALKELPLLKF LGIFNTGLKM FPDLTKVYST DIFFILEITD NPYMTSIPVN AFQGLCNETL TLKLYNNGFT SVQGYAFNGT KLDAVYLNKN KYLTVIDKDA FGGVYSGPSL LLPLGRKSLS FETQKAPRSS MPS
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 21-253 of human TSHR (NP_001018046.1).
    Isotype
    IgG
  • Indications d'application
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    Commentaires

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Yang, Yi, Zhang, He, He, Wu, Xu, Li, Fan, Zhu, Xue, Zhou: "Generation and characterization of a hypothyroidism rat model with truncated thyroid stimulating hormone receptor." dans: Scientific reports, Vol. 8, Issue 1, pp. 4004, (2018) (PubMed).

  • Antigène
    TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))
    Autre désignation
    TSHR (TSHR Produits)
    Synonymes
    anticorps CHNG1, anticorps LGR3, anticorps hTSHR-I, anticorps AI481368, anticorps hypothroid, anticorps hyt, anticorps pet, anticorps TSHRA, anticorps TSH-R, anticorps thyroid stimulating hormone receptor, anticorps tshr, anticorps TSHR, anticorps Tshr
    Sujet
    The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.,TSHR,CHNG1,LGR3,hTSHR-I,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Neuroscience,TSHR
    Poids moléculaire
    28 kDa/30 kDa/86 kDa
    ID gène
    7253
    UniProt
    P16473
    Pathways
    Thyroid Hormone Synthesis
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