RENT1/UPF1 anticorps (AA 270-370)

N° du produit ABIN6149938

Détail du produit anti-RENT1/UPF1 anticorps

Antigène: RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))

Épitope: AA 270-370

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RENT1/UPF1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: KENPSATLED LEKPGVDEEP QHVLLRYEDA YQYQNIFGPL VKLEADYDKK LKESQTQDNI TVRWDLGLNK KRIAYFTLPK TDSDMRLMQG DEICLRYKGD L

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 270-370 of human UPF1/RENT1 (NP_002902.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RENT1/UPF1

Antigène: RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))

Autre désignation: UPF1 (UPF1 Produits)

Synonymes: anticorps HUPF1, anticorps NORF1, anticorps RENT1, anticorps pNORF1, anticorps smg-2, anticorps B430202H16Rik, anticorps PNORF-1, anticorps Rent1, anticorps Upflp, anticorps rent1, anticorps wu:fi40f07, anticorps wu:fj48a01, anticorps zgc:55472, anticorps Tb05.3C6.50, anticorps AO090012000584, anticorps hupf1, anticorps norf1, anticorps pnorf1, anticorps upf1, anticorps UPF1, RNA helicase and ATPase, anticorps UPF1 regulator of nonsense transcripts homolog (yeast), anticorps upf1 regulator of nonsense transcripts homolog (yeast), anticorps regulator of nonsense transcripts 1, anticorps Regulator of nonsense transcripts 1, anticorps UPF1 regulator of nonsense transcripts homolog S homeolog, anticorps UPF1, anticorps Upf1, anticorps upf1, anticorps Tc00.1047053511317.30, anticorps Tb927.5.2140, anticorps TVAG_453890, anticorps TVAG_237840, anticorps AOR_1_1018194, anticorps HPB8_739, anticorps smg-2, anticorps upf1.S

Sujet: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants.,UPF1,HUPF1,NORF1,RENT1,pNORF1,smg-2,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Apoptosis,UPF1

Poids moléculaire: 123 kDa/124 kDa

ID gène: 5976

UniProt: Q92900

Pathways: SARS-CoV-2 Protein Interactome