Urm1 anticorps (AA 1-63)

N° du produit ABIN6149975

Détail du produit anti-Urm1 anticorps

Antigène: Urm1 (Ubiquitin Related Modifier 1 (Urm1))

Épitope: AA 1-63

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Urm1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: MAAPLSVEVE FGGGAELLFD GIKKHRVTLP GQEEPWDIRN LLIWIKKNLL KERPELFIQG DSV

Réactivité croisée: Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-63 of human URM1 (NP_001252511.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Urm1

Antigène: Urm1 (Ubiquitin Related Modifier 1 (Urm1))

Autre désignation: URM1 (Urm1 Produits)

Synonymes: anticorps RGD1306599, anticorps C9orf74, anticorps 2900073H19Rik, anticorps ubiquitin related modifier 1, anticorps ubiquitin related modifier, anticorps ubiquitin-related modifier, anticorps Ubiquitin-related modifier 1 homolog, anticorps Urm1, anticorps LOC733109, anticorps URM1

Sujet: Acts as a sulfur carrier required for 2-thiolation of mcm(5S(2U at tRNA wobble positions of cytosolic tRNA(Lys, tRNA(Glu and tRNA(Gln. Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5S(2U. Also acts as a ubiquitin-like protein (UBL that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.,URM1,C9orf74,URM1

Poids moléculaire: 7 kDa/11 kDa/15 kDa

ID gène: 81605

UniProt: Q9BTM9