UVRAG anticorps (AA 501-699)

N° du produit ABIN6150044

Détail du produit anti-UVRAG anticorps

Antigène: UVRAG (UV Radiation Resistance Associated Gene (UVRAG))

Épitope: AA 501-699

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UVRAG est non-conjugé

Application: Western Blotting (WB)

Séquence: KGHRKRASSE NERLQYKTPP PSYNSALAQP VTTVPSMGET ERKITSLSSS LDTSLDFSKE NKKKGEDLVG SLNGGHANVH PSQEQGEALS GHRATVNGTL LPSEQAGSAS VQLPGEFHPV SEAELCCTVE QAEEIIGLEA TGFASGDQLE AFNCIPVDSA VAVECDEQVL GEFEEFSRRI YALNENVSSF RRPRRSSDK

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 501-699 of human UVRAG (NP_003360.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-UVRAG (ABIN6150044)

Chen, Wu, Sang, Wang, Zong, Sun, Liu, Zhao: "The lncRNA HULC functions as an oncogene by targeting ATG7 and ITGB1 in epithelial ovarian carcinoma." dans: Cell death & disease, Vol. 8, Issue 10, pp. e3118, (2018) (PubMed).

Détails sur UVRAG

Antigène: UVRAG (UV Radiation Resistance Associated Gene (UVRAG))

Autre désignation: UVRAG (UVRAG Produits)

Synonymes: anticorps DHTX, anticorps VPS38, anticorps p63, anticorps 9530039D02Rik, anticorps AI648770, anticorps BB124205, anticorps Uvrag1, anticorps Uvragl, anticorps zgc:56164, anticorps uvrag, anticorps MGC81810, anticorps UVRAG, anticorps MGC131135, anticorps CG6116, anticorps Dmel\\CG6116, anticorps UV radiation resistance associated, anticorps UV radiation resistance associated gene, anticorps UV radiation resistance associated S homeolog, anticorps UV radiation resistance associated L homeolog, anticorps UV-resistance associated gene, anticorps UVRAG, anticorps Uvrag, anticorps uvrag, anticorps uvrag.S, anticorps uvrag.L

Sujet: This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.,UVRAG,DHTX,VPS38,p63,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Autophagy,Cardiovascular,Heart,Regulators,UVRAG

Poids moléculaire: 35 kDa/78 kDa

ID gène: 7405

UniProt: Q9P2Y5