WISP2 anticorps (AA 1-250)

N° du produit ABIN6150227

Détail du produit anti-WISP2 anticorps

Antigène: WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))

Épitope: AA 1-250

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WISP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: MRGTPKTHLL AFSLLCLLSK VRTQLCPTPC TCPWPPPRCP LGVPLVLDGC GCCRVCARRL GEPCDQLHVC DASQGLVCQP GAGPGGRGAL CLLAEDDSSC EVNGRLYREG ETFQPHCSIR CRCEDGGFTC VPLCSEDVRL PSWDCPHPRR VEVLGKCCPE WVCGQGGGLG TQPLPAQGPQ FSGLVSSLPP GVPCPEWSTA WGPCSTTCGL GMATRVSNQN RFCRLETQRR LCLSRPCPPS RGRSPQNSAF

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human WISP2 (NP_003872.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur WISP2

Antigène: WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))

Autre désignation: WISP2 (WISP2 Produits)

Synonymes: anticorps MGC84196, anticorps WISP2, anticorps ccn5, anticorps CCN5, anticorps CT58, anticorps CTGF-L, anticorps Ccn5, anticorps Crgr4, anticorps Ctgfl, anticorps Rcop1, anticorps WNT1 inducible signaling pathway protein 2, anticorps WNT1 inducible signaling pathway protein 2 S homeolog, anticorps WISP2, anticorps wisp2.S, anticorps wisp2, anticorps Wisp2

Sujet: This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72 % identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.,WISP2,CCN5,CT58,CTGF-L,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Stem Cells,Mesenchymal Stem Cells,Cardiovascular,Heart,Hypertrophy,WISP2

Poids moléculaire: 22 kDa/26 kDa

ID gène: 8839

UniProt: O76076

Pathways: Signalisation WNT, Growth Factor Binding