RECQL2 anticorps (AA 1223-1432)

N° du produit ABIN6150263

Détail du produit anti-RECQL2 anticorps

Antigène: RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))

Épitope: AA 1223-1432

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RECQL2 est non-conjugé

Application: Western Blotting (WB)

Séquence: CQTNSVQTDL FSSTKPQEEQ KTSLVAKNKI CTLSQSMAIT YSLFQEKKMP LKSIAESRIL PLMTIGMHLS QAVKAGCPLD LERAGLTPEV QKIIADVIRN PPVNSDMSKI SLIRMLVPEN IDTYLIHMAI EILKHGPDSG LQPSCDVNKR RCFPGSEEIC SSSKRSKEEV GINTETSSAE RKRRLPVWFA KGSDTSKKLM DKTKRGGLFS

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1223-1432 of human WRN (NP_000544.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:1000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RECQL2

Antigène: RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))

Autre désignation: WRN (WRN Produits)

Sujet: This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3' to 5' DNA helicase activity, and is also a 3' to 5' exonuclease. Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing, this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by premature aging.,WRN,RECQ3,RECQL2,RECQL3,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cell Biology & Developmental Biology,Apoptosis,WRN

Poids moléculaire: 162 kDa

ID gène: 7486

UniProt: Q14191

Pathways: Réparation de l'ADN