Coagulation Factor X anticorps

N° du produit ABIN615558

Détail du produit anti-Coagulation Factor X anticorps

Antigène: Coagulation Factor X (F10)

Reactivité: Humain

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp Coagulation Factor X est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunoelectrophoresis (IEP), Immunodiffusion (ID)

Specificité: This antibody detects Coagulation factor X (F10). Only one arc was seen with normal plasma. No arc was seen with Factor X deficient plasma.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogène: Human Factor X purified from plasma, activated and active site blocked

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: 10 mM HEPES, pH 7.4, 0.15 M Sodium Chloride, 50 % Glycerol

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Coagulation Factor X

Antigène: Coagulation Factor X (F10)

Abstract: F10 Produits

Synonymes: anticorps FX, anticorps FXA, anticorps Cf10, anticorps fX, anticorps fi12c10, anticorps wu:fi12c10, anticorps F10, anticorps f10, anticorps coagulation factor X, anticorps Coagulation factor X, anticorps coagulation factor 10 L homeolog, anticorps F10, anticorps f10, anticorps CpipJ_CPIJ012712, anticorps CpipJ_CPIJ014863, anticorps CpipJ_CPIJ016937, anticorps CpipJ_CPIJ017791, anticorps fa10, anticorps f10.L

Sujet: F10 is the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds, the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting.Synonyms: Stuart factor, Stuart-Prower factor

ID gène: 2159

NCBI Accession: NP_000495

UniProt: P00742