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KRT1 anticorps (CF®568)

KRT1 Reactivité: Humain, Rat, Souris, Lapin, Poulet, Boeuf (Vache), Singe, Chien WB, IF, FACS, IHC (f) Hôte: Souris Monoclonal AE-3 CF®568
N° du produit ABIN6161979
  • Antigène Voir toutes KRT1 Anticorps
    KRT1 (Cytokeratin HMW (KRT1))
    Reactivité
    • 27
    • 27
    • 18
    • 9
    • 9
    • 9
    • 9
    • 8
    • 1
    Humain, Rat, Souris, Lapin, Poulet, Boeuf (Vache), Singe, Chien
    Hôte
    • 27
    Souris
    Clonalité
    • 27
    Monoclonal
    Conjugué
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    Cet anticorp KRT1 est conjugé à/à la CF®568
    Application
    • 26
    • 26
    • 17
    • 15
    • 9
    • 9
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Fonction
    Mouse Monoclonal anti-Cytokeratin, HMW (AE-3), CF568 Conjugate
    Attributs du produit
    This MAb recognizes basic (Type II or HMW) cytokeratins, which include 67 kDa (CK1), 64 kDa (CK3), 59 kDa (CK4), 58 kDa (CK5), 56 kDa (CK6), 52 kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50 , 48, 46, 45, and 40 kDa. MAb AE3 recognizes the 65-67, 64, 59, 58, 56, and 52 kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    Immunogène
    Human epidermal keratin
    Clone
    AE-3
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product KRT1 Anticorps primaire
  • Indications d'application
    Immunohistology formalin-fixed 0.25-0.5 μg/mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Immunofluorescence 1-2 μg/mL
    • Western blotting 0.5-1 μg/mL
    • Optimal dilution for a specific application should be determined by user
    Commentaires

    Epithelial cells, Skin or Adenocarcinomas

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    100 μg/mL
    Buffer
    PBS/0.1 % BSA/0.05 % azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Protect from light
  • Antigène
    KRT1 (Cytokeratin HMW (KRT1))
    Autre désignation
    Cytokeratin, HMW (KRT1 Produits)
    Synonymes
    anticorps CK1, anticorps EHK, anticorps EHK1, anticorps EPPK, anticorps K1, anticorps KRT1A, anticorps NEPPK, anticorps keratin 1, anticorps KRT1
    Sujet
    KRT2B, KRT2P, HUMCYT2A, Keratin, type II Cytoskeletal 2 oral, K76, Keratin 2p (K2P), Keratin-76, Cytokeratin-2P (CK-2P, Type-II Keratin Kb9
    Poids moléculaire
    52-67 kDa
    ID gène
    51350, 654392
    UniProt
    Q01546
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