Plakophilin 1 anticorps (N-Term) (CF®488A)
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- Antigène Voir toutes Plakophilin 1 (PKP1) Anticorps
- Plakophilin 1 (PKP1)
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Épitope
- N-Term
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Reactivité
- Humain, Souris
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Plakophilin 1 est conjugé à/à la CF®488A
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Application
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
- Fonction
- Mouse Monoclonal anti-Plakophilin-1 (10B2), CF488A Conjugate
- Attributs du produit
- This antibody recognizes a protein of 75 kDa, identified as Plakophilin-1. Its epitope maps between aa 1-27 human Plakophilin-1. Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogène
- N-terminus of human Plakophilin-1 protein (exact sequence is proprietary)
- Clone
- 10B2
- Isotype
- IgG1
- Top Product
- Discover our top product PKP1 Anticorps primaire
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- Indications d'application
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Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- Commentaires
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HaCat Cells.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Protect from light
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- Antigène
- Plakophilin 1 (PKP1)
- Autre désignation
- Plakophilin-1 (PKP1 Produits)
- Synonymes
- anticorps PKP1, anticorps fb30d08, anticorps wu:fb30d08, anticorps AI528551, anticorps B6P, anticorps plakophilin 1, anticorps plakophilin 1b, anticorps PKP1, anticorps pkp1b, anticorps Pkp1
- Sujet
- B6P, B, 6 protein, PKP1, Plakophilin-1 (ectodermal dysplasia/skin fragility syndrome)
- Poids moléculaire
- 75 kDa
- ID gène
- 5317, 497350
- UniProt
- Q13835
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