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CD19 anticorps

CD19 Reactivité: Souris FACS, IP, IHC (fro), Func Hôte: Rat Monoclonal 1D3 unconjugated
N° du produit ABIN616757
  • Antigène Voir toutes CD19 Anticorps
    CD19 (CD19 Molecule (CD19))
    Reactivité
    • 293
    • 166
    • 41
    • 29
    • 19
    • 10
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Souris
    Hôte
    • 185
    • 130
    • 57
    • 4
    Rat
    Clonalité
    • 257
    • 115
    • 2
    Monoclonal
    Conjugué
    • 127
    • 25
    • 22
    • 22
    • 19
    • 10
    • 9
    • 8
    • 8
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD19 est non-conjugé
    Application
    • 265
    • 117
    • 74
    • 70
    • 52
    • 52
    • 23
    • 21
    • 14
    • 14
    • 10
    • 10
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    • 3
    • 3
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    • 2
    • 2
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    • 2
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    • 1
    • 1
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    • 1
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    • 1
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    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
    Specificité
    This antibody detects detects mouse CD19, 95 kDa type I transmembrane glycoprotein (immunoglobulin superfamily) expressed on B lymphocytes and follicular dendritic cells, it is lost on plasma cells.
    Réactivité croisée (Details)
    Species reactivity (tested):Mouse
    Purification
    Protein-G affinity chromatography
    niveau d'endotoxine
    Less than 10 EU/mg of the protein, as determined by the LAL test
    Immunogène
    Mouse CD19-transfected cell line
    Clone
    1D3
    Isotype
    IgG2a
    Top Product
    Discover our top product CD19 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Azide free PBS, pH ~7.4
    Agent conservateur
    Azide free
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    CD19 (CD19 Molecule (CD19))
    Autre désignation
    CD19 (CD19 Produits)
    Sujet
    CD19 is a transmembrane glycoprotein of Ig superfamily expressed by B cells from the time of heavy chain rearrangement until plasma cell differentiation. It forms a tetrameric complex with CD21 (complement receptor type 2), CD81 (TAPA-1) and Leu13. Together with BCR (B cell antigen receptor), this complex signals to decrease B cell treshold for activation by the antigen. Besides being signal-amplifying coreceptor for BCR, CD19 can also signal independently of BCR coligation and it turns out to be a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.Synonyms: B-cell marker, B-lymphocyte surface antigen B4, Differentiation antigen CD19, Leu-12
    ID gène
    12478
    NCBI Accession
    NP_033974
    UniProt
    P25918
    Pathways
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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