CD37 anticorps
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- Antigène Voir toutes CD37 (TSPAN26) Anticorps
- CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD37 est non-conjugé
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Application
- Flow Cytometry (FACS), Immunofluorescence (IF)
- Fonction
- Mouse Monoclonal anti-CD37 (IPO-24), Purified, with BSA
- Attributs du produit
- This antibody recognizes a protein of 33-55 kDa, identified as CD37 (Workshop V, Code CD37.7). CD37 is strongly expressed on normal and neoplastic mature (sIg ) B-lymphocytes. In B-cell ontogeny, CD37 appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells.1 CD37 is also present, at low densities, on resting and activated T cells, neutrophils, monocytes, and some myelomonocytic leukemia cells. It is absent from platelets, erythrocytes. CD37 is a member of a family of tetraspan transmembrane proteins, including CD9, CD53, CD63, CD81, and CD82. It associates other tetraspan transmembrane proteins and MHC class II molecules to form a large complex at the surface of B cells and play a role in signal transduction. CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies like B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkin'' lymphoma (B-NHL). Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Purification
- Purified
- Immunogène
- Spleen cells of a patient with hairy cell leukemia
- Clone
- IPO-24
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product TSPAN26 Anticorps primaire
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- Indications d'application
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Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
- Commentaires
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Daudi, Raji, Namalva, Ramos cells and human lymphocytes. Human tonsil and lymph node.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 200 μg/mL
- Buffer
- PBS/0.05 % BSA/0.05 % azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Antigène
- CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
- Autre désignation
- CD37 (TSPAN26 Produits)
- Synonymes
- anticorps Tspan26, anticorps GP52-40, anticorps TSPAN26, anticorps CD37 antigen, anticorps CD37 molecule, anticorps Cd37, anticorps CD37
- Sujet
- Cell differentiation antigen 37, GP52 40, Tetraspanin-26, Tspan-26, TSPAN26
- Poids moléculaire
- 33-55 kDa
- ID gène
- 951, 166556
- UniProt
- P11049
- Pathways
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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