Serotonin Receptor 5A anticorps (AA 17-34)

N° du produit ABIN617921

Détail du produit anti-Serotonin Receptor 5A anticorps

Antigène: Serotonin Receptor 5A (HTR5A)

Épitope: AA 17-34

Reactivité: Rat, Clams (Mytilus)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Serotonin Receptor 5A est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoelectron Microscopy (IEM)

Réactivité croisée: Souris, Rat (Rattus)

Attributs du produit: The 5-HT 5A Receptor Antibody was raised against synthetic peptide sequence corresponding to amino acids 17-34 of the rat 5-HT5A receptor coupled to carrier protein with glutaraldehyde. The 5-HT5A Receptor was quality control tested using standard immunohisto-chemical methods. The antiserum demonstrates strongly positive labeling of rat cortex and hippocampus using indirect immunofluorescent and biotin/avidin-HRP techniques. Recommended primary dilutions are 1/100 - 1/300 in PBS/0.3 % Triton X-100 - Cy3 and 1/200 - 1/400 in PBS/0.3 % Triton X-100 - Bn/Av-HRP. Intensification methods such as nickel will approximately double the dilution factor as recommended. The antibody was characterized by immunoblotting and immunohistochemistry. Immunoblots of rat brain extracts revealed the presence of two bands at molecular weights of 41 and 47 kD. The lower weight band agrees with the calculated molecular weight based on amino acid sequence. The higher weight may represent glycosylated receptor protein. Immunohistochemical staining of rat brain correlates well with Northern blot analysis and in situ hybridization studies. Immunolabeling is completely abolished by preadsorption with synthetic rat 5-HT5A receptor (17-34). BlastP database sequence homology searches indicate that the amino acid sequence is unique to rat and mouse 5-HT5A receptor.

Purification: Affinity Purified

Immunogène: Rat 5-HT5A receptor (17-34)

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Contains ≤ 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: After reconstitution, use immediately or refrigerate at 2 - 8 °C up to 2 days. For long-term storage aliquot antibody and freeze at -15 °C or lower. Avoid repeated freeze/thaw cycles.

Références pour anticorps anti-Serotonin Receptor 5A (ABIN617921)

Kreiling, Stephens, Reinisch: "A mixture of environmental contaminants increases cAMP-dependent protein kinase in Spisula embryos." dans: Environmental toxicology and pharmacology, Vol. 19, Issue 1, pp. 9-18, (2011) (PubMed).

Doly, Fischer, Brisorgueil, Vergé, Conrath: "5-HT5A receptor localization in the rat spinal cord suggests a role in nociception and control of pelvic floor musculature." dans: The Journal of comparative neurology, Vol. 476, Issue 4, pp. 316-29, (2004) (PubMed).

Détails sur Serotonin Receptor 5A

Antigène: Serotonin Receptor 5A (HTR5A)

Abstract: HTR5A Produits

Synonymes: anticorps HTR5A, anticorps si:dkey-265a7.5, anticorps Htr5, anticorps 5-HT5A, anticorps 5HT5A, anticorps MR22, anticorps 5-hydroxytryptamine receptor 5A, anticorps 5-hydroxytryptamine (serotonin) receptor 5A, genome duplicate a, anticorps 5-hydroxytryptamine (serotonin) receptor 5A, anticorps HTR5A, anticorps htr5aa, anticorps Htr5a

Sujet: Other Names:
5-hydroxytryptamine receptor 5A, 5-HT5A, REC17,5ht5a,MR22,5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled

ID gène: 25689

Pathways: Signalistation JAK/STAT