Nkx2-2 anticorps (CF®594)
-
- Antigène Voir toutes Nkx2-2 Anticorps
- Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
-
Reactivité
- Humain, Souris, Rat, Poulet
-
Hôte
- Souris
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp Nkx2-2 est conjugé à/à la CF®594
-
Application
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Fonction
- Mouse Monoclonal anti-NKX2.2 (NX2/294), CF594 Conjugate
- Attributs du produit
- Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93 % and a specificity of 89 %, and aids in the differential diagnosis of small round cell tumors. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogène
- Human full-length recombinant NKX2.2 protein
- Clone
- NX2-294
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product Nkx2-2 Anticorps primaire
-
-
- Indications d'application
-
Immunohistology formalin-fixed 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Optimal dilution for a specific application should be determined by user
- Commentaires
-
Pancreas or Ewing s sarcoma
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Protect from light
-
- Antigène
- Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
- Autre désignation
- NKX2.2 (Nkx2-2 Produits)
- Synonymes
- anticorps XeNK-2, anticorps Xnkx2.2, anticorps nkx2-2-A, anticorps nkx2.2, anticorps NKX-2.2, anticorps NKX2.2, anticorps NKX2B, anticorps Nkx-2.2, anticorps Nkx2.2, anticorps tinman, anticorps id:ibd5090, anticorps nk2.2, anticorps nkx2-2, anticorps wu:fc83b01, anticorps zgc:136536, anticorps NK2 homeobox 2 S homeolog, anticorps NK2 homeobox 2, anticorps NK2 homeobox 2a, anticorps nkx2-2.S, anticorps NKX2-2, anticorps Nkx2-2, anticorps nkx2.2a
- Sujet
- Homeobox protein NK-2 homolog B, NK2 transcription factor like protein B, NK2 transcription factor related locus 2, NKX22, Nkx2b, tinman
- Poids moléculaire
- 40-50 kDa
- ID gène
- 4821, 516922
- UniProt
- O95096
- Pathways
- Dopaminergic Neurogenesis
-