LGALS13 anticorps (AA 23-134) (CF®488A)

N° du produit ABIN6189444

Détail du produit anti-LGALS13 anticorps (CF®488A)

Antigène: LGALS13 (Lectin, Galactoside-Binding, Soluble, 13 (LGALS13))

Épitope: AA 23-134

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LGALS13 est conjugé à/à la CF®488A

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), ELISA, Coating (Coat)

Fonction: Mouse Monoclonal anti-Galectin-13 / Placental-Protein-13 (PP13/1162), CF488A Conjugate

Attributs du produit: This antibody recognizes a 32 kDa protein, which is identified as homodimer of galectin-13 (also known as PP13). Galectins are a family of soluble ?-galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, galectin-13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, galectin-13 exists as a disulfide-linked homodimer. Galectin-13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for galectin-13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant human Galectin-13 protein fragment (aa23-134) (exact sequence is proprietary)

Clone: PP13-1162

Isotype: IgG2b

Information d'application

Indications d'application: Immunohistology (formalin) 0.5-1 μg/mL

• Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris, 1 mM EDTA  pH 9.0 or 10 mM citrate buffer  pH 6.0 for 10-20 min followed by cooling at RT for 20 min
• Immunofluorescence 0.5-1 μg/mL
• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• ELISA For coating, order Ab without BSA
• Optimal dilution for a specific application should be determined by user

Commentaires:

K-562 cells. Placenta or Spleen.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur LGALS13

Antigène: LGALS13 (Lectin, Galactoside-Binding, Soluble, 13 (LGALS13))

Autre désignation: Galectin-13 / Placental-Protein-13 (LGALS13 Produits)

Synonymes: anticorps GAL13, anticorps PLAC8, anticorps PP13, anticorps Gal-11, anticorps Gal-13, anticorps Gal11, anticorps gal-13, anticorps galectin 13, anticorps avian beta-defensin 13, anticorps LGALS13, anticorps AvBD13

Sujet: Gal-13, GAL13, Galactoside-binding soluble lectin 13, Galectin-13, Galectin13, Lectin galactoside binding soluble 13, LGALS13, PLAC8, Placental protein 13 (PP13), Placental tissue protein 13

Poids moléculaire: 16 kDa (monomer), 32 kDa (homodimer)

ID gène: 29124, 23671

UniProt: Q9UHV8