Melanoma gp100 anticorps (CF®405S)
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- Antigène Voir toutes Melanoma gp100 (PMEL) Anticorps
- Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Melanoma gp100 est conjugé à/à la CF®405S
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- Fonction
- Mouse Monoclonal anti-Pmel17 / gp100 / SILV (HMB45), CF405S Conjugate
- Attributs du produit
- By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. Metastatic amelanotic melanoma can often be confused with a variety of poorly differentiated carcinomas, large cell lymphomas, and sarcomas using H & E stains alone. It is also difficult to differentiate melanoma from spindle cell carcinomas and various types of mesenchymal neoplasms. This MAb stains fetal and neonatal melanocytes, junctional and blue nevus cells, and malignant melanoma. This MAb also stains Angiomyolipoma (PEComa). Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogène
- Extract of pigmented melanoma metastases from lymph nodes
- Clone
- HMB45
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product PMEL Anticorps primaire
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- Indications d'application
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Immunohistology (formalin)
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Does not react with dog or rat, others not tested
- Optimal dilution for a specific application should be determined by user
- Commentaires
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SK-MEL-28 cells or Melanoma
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Protect from light
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- Antigène
- Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
- Autre désignation
- Pmel17 / gp100 / SILV (PMEL Produits)
- Synonymes
- anticorps D12S53E, anticorps ME20, anticorps ME20-M, anticorps ME20M, anticorps P1, anticorps P100, anticorps PMEL17, anticorps SI, anticorps SIL, anticorps SILV, anticorps gp100, anticorps D10H12S53E, anticorps D12S53Eh, anticorps Pmel17, anticorps Si, anticorps Silv, anticorps gp87, anticorps RPE1, anticorps MMP115, anticorps silverb, anticorps silver, anticorps cb397, anticorps fdv, anticorps pmel17, anticorps sb:cb397, anticorps silva, anticorps wu:fc11g11, anticorps wu:fj24g11, anticorps zgc:136622, anticorps premelanosome protein, anticorps premelanosome protein b, anticorps premelanosome protein a, anticorps PMEL, anticorps Pmel, anticorps pmelb, anticorps pmela
- Poids moléculaire
- 90-100 kDa
- ID gène
- 6490, 95972
- UniProt
- P40967
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