MUTYH anticorps
-
- Antigène Voir toutes MUTYH Anticorps
- MUTYH (MutY Homolog (E. Coli) (MUTYH))
-
Reactivité
- Humain, Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp MUTYH est non-conjugé
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human MUTYH
- Isotype
- IgG
- Top Product
- Discover our top product MUTYH Anticorps primaire
-
-
- Indications d'application
- Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid freeze / thaw cycles
- Stock
- -20 °C/-80 °C
-
- Antigène
- MUTYH (MutY Homolog (E. Coli) (MUTYH))
- Autre désignation
- MUTYH (MUTYH Produits)
- Synonymes
- anticorps MUTYH, anticorps MGC145569, anticorps CYP2C, anticorps MYH, anticorps 5730495A01Rik, anticorps Mutyha, anticorps Mutyhalpha, anticorps Mutyhb, anticorps Mutyhbeta, anticorps Mutyhc, anticorps Myh, anticorps mutY DNA glycosylase, anticorps mutY homolog (E. coli), anticorps A/G-specific adenine DNA glycosylase-like, anticorps MUTYH, anticorps mutyh, anticorps LOC100373318, anticorps Mutyh
- Sujet
-
Base excision repair (BER) proteins catalyze the removal of incorrect or damaged bases, including oxidized bases, from DNA. N-glycosylases specific to a given lesion remove the incorrect base as the first step in BER. MYH is the mammalian ortholog of E. coli MutY, a DNA glycosylase that catalyzes the removal of 8-oxoG:A mismatches. Several MYH isoforms have been detected in human cells localizing to either the nucleus or the mitochondria. MYH interacts with DNA repair proteins and localizes to DNA damage foci after oxidative damage. Research studies have shown that mutations in the corresponding MYH gene are associated with human gastric and colorectal cancers.
Synonyms: MGC4416, MYH - ID gène
- 4595
- UniProt
- Q9UIF7
- Pathways
- Réparation de l'ADN
-