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PTEN anticorps (pSer229)

PTEN Reactivité: Humain DB Hôte: Lapin Polyclonal RB39748 unconjugated
N° du produit ABIN6241047
  • Antigène Voir toutes PTEN Anticorps
    PTEN (Phosphatase and Tensin Homolog (PTEN))
    Épitope
    • 18
    • 17
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer229
    Reactivité
    • 46
    • 17
    • 17
    Humain
    Hôte
    • 45
    • 1
    Lapin
    Clonalité
    • 45
    • 1
    Polyclonal
    Conjugué
    • 31
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PTEN est non-conjugé
    Application
    • 26
    • 20
    • 15
    • 14
    • 13
    • 13
    • 6
    • 5
    • 3
    • 3
    Dot Blot (DB)
    Homologie
    M
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This PTEN Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S229 of human PTEN.
    Clone
    RB39748
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PTEN Anticorps primaire
  • Indications d'application
    DB: 1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Antigène
    PTEN (Phosphatase and Tensin Homolog (PTEN))
    Autre désignation
    PTEN (PTEN Produits)
    Synonymes
    anticorps 10q23del, anticorps BZS, anticorps CWS1, anticorps DEC, anticorps GLM2, anticorps MHAM, anticorps MMAC1, anticorps PTEN1, anticorps TEP1, anticorps 2310035O07Rik, anticorps A130070J02Rik, anticorps AI463227, anticorps B430203M17Rik, anticorps Mmac, anticorps PTENP1, anticorps wu:fc52g04, anticorps zgc:73086, anticorps fa11a08, anticorps fb73f10, anticorps fc83f12, anticorps fd16b10, anticorps fk90e11, anticorps pten, anticorps si:bz1g13.4, anticorps wu:fa11a08, anticorps wu:fb73f10, anticorps wu:fc83f12, anticorps wu:fd16b10, anticorps wu:fk90e11, anticorps phosphatase and tensin homolog, anticorps phosphatase and tensin homolog L homeolog, anticorps phosphatase and tensin homolog A, anticorps phosphatase and tensin homolog B, anticorps PTEN, anticorps Pten, anticorps pten.L, anticorps ptena, anticorps ptenb
    Sujet
    This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.
    Poids moléculaire
    47166
    NCBI Accession
    NP_000305
    UniProt
    P60484
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Inositol Metabolic Process, Synaptic Membrane, Regulation of Cell Size, Autophagy, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
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