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FEN1 anticorps

FEN1 Reactivité: Humain, Souris WB, IP Hôte: Souris Monoclonal unconjugated
N° du produit ABIN6241658
  • Antigène Voir toutes FEN1 Anticorps
    FEN1 (Flap Structure-Specific Endonuclease 1 (FEN1))
    Reactivité
    • 63
    • 43
    • 38
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 59
    • 8
    Souris
    Clonalité
    • 57
    • 10
    Monoclonal
    Conjugué
    • 43
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FEN1 est non-conjugé
    Application
    • 55
    • 17
    • 16
    • 13
    • 12
    • 11
    • 9
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Immunogène
    Recombinant Protein
    Top Product
    Discover our top product FEN1 Anticorps primaire
  • Indications d'application
    IP: 1:500. WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Stock
    4 °C,-20 °C
  • Antigène
    FEN1 (Flap Structure-Specific Endonuclease 1 (FEN1))
    Autre désignation
    FEN-1 (FEN1 Produits)
    Synonymes
    anticorps FEN-1, anticorps FEN1, anticorps AW538437, anticorps MF1, anticorps RAD2, anticorps cb879, anticorps fen-1, anticorps fen1, anticorps mf1, anticorps rad2, anticorps xFEN1a, anticorps flap structure-specific endonuclease 1, anticorps flap endonuclease 1-like, anticorps Flap endonuclease-1, anticorps 5'-3' exonuclease family protein, anticorps flap structure specific endonuclease 1, anticorps flap structure-specific endonuclease 1 L homeolog, anticorps nuclease, Rad2 family, anticorps FEN1, anticorps LOC100808044, anticorps Bm1_49605, anticorps AT5G26680, anticorps Fen1, anticorps fen1, anticorps fen1.L
    Sujet
    Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double- stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
    UniProt
    P39748
    Pathways
    Telomere Maintenance, Réparation de l'ADN, DNA Replication, Synthesis of DNA
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