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p130 anticorps

RBL2 Reactivité: Humain, Rat, Souris WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6241739
  • Antigène Voir toutes p130 (RBL2) Anticorps
    p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))
    Reactivité
    • 70
    • 28
    • 26
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 63
    • 8
    Lapin
    Clonalité
    • 64
    • 7
    Polyclonal
    Conjugué
    • 30
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp p130 est non-conjugé
    Application
    • 31
    • 28
    • 14
    • 13
    • 13
    • 7
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Immunogène
    synthetic peptide
    Top Product
    Discover our top product RBL2 Anticorps primaire
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Stock
    4 °C,-20 °C
  • Antigène
    p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))
    Autre désignation
    RB2 (RBL2 Produits)
    Synonymes
    anticorps RBL2, anticorps RBR2, anticorps RRB2a, anticorps PRB2, anticorps RBR-2, anticorps Rb2, anticorps p130, anticorps P130, anticorps retinoblastoma-like 2 (p130), anticorps RB transcriptional corepressor like 2, anticorps related to retinoblastoma 2, anticorps RBL2, anticorps LOC541652, anticorps Rbl2
    Sujet
    Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. May act as a tumor suppressor.
    UniProt
    Q08999
    Pathways
    Cycle Cellulaire, Mitotic G1-G1/S Phases
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