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HGS anticorps

HGS Reactivité: Humain, Souris, Rat WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6241891
  • Antigène Voir toutes HGS Anticorps
    HGS (Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS))
    Reactivité
    • 44
    • 30
    • 21
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 38
    • 5
    • 1
    Lapin
    Clonalité
    • 41
    • 3
    Polyclonal
    Conjugué
    • 32
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HGS est non-conjugé
    Application
    • 36
    • 21
    • 19
    • 15
    • 10
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Immunogène
    Synthetic Peptide
    Top Product
    Discover our top product HGS Anticorps primaire
  • Indications d'application
    IF: 1:100. WB: 1:1000. IHC: 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Stock
    4 °C,-20 °C
  • Antigène
    HGS (Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS))
    Autre désignation
    HGS (HGS Produits)
    Synonymes
    anticorps HRS, anticorps Hrs, anticorps fi34f05, anticorps zgc:63492, anticorps wu:fi34f05, anticorps Hgr, anticorps ZFYVE8, anticorps CG2903, anticorps Dmel\\CG2903, anticorps HRS-2, anticorps Vps27, anticorps hrs, anticorps l(2)23AB5, anticorps l(2)23Ad, anticorps l(2)23Ad(Hrs), anticorps vps27, anticorps hgs, anticorps hepatocyte growth factor-regulated tyrosine kinase substrate, anticorps HGF-regulated tyrosine kinase substrate, anticorps Hepatocyte growth factor regulated tyrosine kinase substrate, anticorps hepatocyte growth factor-regulated tyrosine kinase substrate L homeolog, anticorps HGS, anticorps Hgs, anticorps hgs, anticorps Hrs, anticorps hgs.L
    Sujet
    Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin-coated regions. Involved in down- regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes. May contribute to the efficient recruitment of SMADs to the activin receptor complex. Involved in receptor recycling via its association with the CART complex, a multiprotein complex required for efficient transferrin receptor recycling but not for EGFR degradation.
    UniProt
    O14964
    Pathways
    EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Synaptic Vesicle Exocytosis, EGFR Downregulation
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