KAP1 anticorps
-
- Antigène Voir toutes KAP1 (TRIM28) Anticorps
- KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))
-
Reactivité
- Humain
-
Hôte
- Souris
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp KAP1 est non-conjugé
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)
- Immunogène
- Recombinant Protein
- Top Product
- Discover our top product TRIM28 Anticorps primaire
-
anti-Tripartite Motif Containing 28 (TRIM28) (AA 379-524) antibody
TRIM28 Reactivité: Humain WB, ELISA, IF, IHC (p), RNAi Hôte: Souris Monoclonal 4E6 unconjugated
anti-Tripartite Motif Containing 28 (TRIM28) (N-Term) antibodyTRIM28 Reactivité: Humain WB, IF, IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
anti-Tripartite Motif Containing 28 (TRIM28) antibodyTRIM28 Reactivité: Humain WB, IF, IP, IHC (p), ICC, ChIP Hôte: Lapin Polyclonal unconjugated
anti-Tripartite Motif Containing 28 (TRIM28) (AA 576-835) antibodyTRIM28 Reactivité: Humain WB, IHC, IF, IP Hôte: Lapin Polyclonal unconjugated
anti-Tripartite Motif Containing 28 (TRIM28) (C-Term) antibodyVerified TRIM28 Reactivité: Humain ELISA, IHC, IF, FACS Hôte: Chèvre Polyclonal unconjugated
anti-Tripartite Motif Containing 28 (TRIM28) (AA 379-524) antibodyTRIM28 Reactivité: Humain WB, ELISA, IHC (p) Hôte: Souris Monoclonal 1D11 unconjugated
anti-Tripartite Motif Containing 28 (TRIM28) (AA 22-291) antibodyTRIM28 Reactivité: Humain WB, ELISA, IHC, IP Hôte: Lapin Polyclonal unconjugated
anti-Tripartite Motif Containing 28 (TRIM28) (AA 178-207), (N-Term) antibodyTRIM28 Reactivité: Humain WB, IF, IHC (p) Hôte: Lapin Polyclonal RB09760 unconjugated
anti-Tripartite Motif Containing 28 (TRIM28) antibodyTRIM28 Reactivité: Humain, Souris, Rat IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Tripartite Motif Containing 28 (TRIM28) (pSer824) antibodyTRIM28 Reactivité: Humain, Souris, Rat WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
-
- Indications d'application
- IP: 1:500. WB: 1:1000. IHC: 1:100. ICC: 1:100
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Stock
- 4 °C,-20 °C
-
- Antigène
- KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))
- Autre désignation
- KAP1 / TIF1 beta (TRIM28 Produits)
- Sujet
- Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression. Recruitment of SETDB1 induces heterochromatinization. May play a role as a coactivator for CEBPB and NR3C1 in the transcriptional activation of ORM1. Also corepressor for ERBB4. Inhibits E2F1 activity by stimulating E2F1-HDAC1 complex formation and inhibiting E2F1 acetylation. May serve as a partial backup to prevent E2F1-mediated apoptosis in the absence of RB1. Important regulator of CDKN1A/p21(CIP1). Has E3 SUMO-protein ligase activity toward itself via its PHD-type zinc finger. Also specifically sumoylates IRF7, thereby inhibiting its transactivation activity. Ubiquitinates p53/TP53 leading to its proteosomal degradation, the function is enhanced by MAGEC2 and MAGEA2, and possibly MAGEA3 and MAGEA6. Mediates the nuclear localization of KOX1, ZNF268 and ZNF300 transcription factors.
- UniProt
- Q13263
- Pathways
- Signalisation Hedgehog, Positive Regulation of Response to DNA Damage Stimulus
-
