SMC1A anticorps (C-Term)
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- Antigène Voir toutes SMC1A Anticorps
- SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp SMC1A est non-conjugé
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Application
- Western Blotting (WB), Immunocytochemistry (ICC)
- Immunogène
- Recombinant Protein
- Top Product
- Discover our top product SMC1A Anticorps primaire
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- Indications d'application
- WB: 1:1000. ICC: 1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Stock
- 4 °C,-20 °C
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- Antigène
- SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))
- Autre désignation
- SMC1A (SMC1A Produits)
- Synonymes
- anticorps CDLS2, anticorps DXS423E, anticorps SB1.8, anticorps SMC1, anticorps SMC1L1, anticorps SMC1alpha, anticorps SMCB, anticorps SMC-1A, anticorps NV15570, anticorps 5830426I24Rik, anticorps Sb1.8, anticorps Smc1, anticorps Smc1alpha, anticorps Smc1l1, anticorps Smcb, anticorps mKIAA0178, anticorps smc1, anticorps smc1a, anticorps smc1l1, anticorps xSMC1, anticorps smc1aa, anticorps structural maintenance of chromosomes 1A, anticorps structural maintenance of chromosomes 1A b, anticorps structural maintenance of chromosomes 1A L homeolog, anticorps SMC1A, anticorps smc1a, anticorps Smc1a, anticorps smc1ab, anticorps smc1a.L
- Sujet
- Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Involved in DNA repair via its interaction with BRCA1 and its related phosphorylation by ATM, or via its phosphorylation by ATR. Works as a downstream effector both in the ATM/NBS1 branch and in the ATR/MSH2 branch of S-phase checkpoint.
- UniProt
- Q14683
- Pathways
- Stem Cell Maintenance
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